Search for dissertations about: "lineage commitment"
Showing result 6 - 10 of 54 swedish dissertations containing the words lineage commitment.
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6. Generation of Retinal Neurons : Focus on the Proliferation and Differentiation of the Horizontal Cells and their Subtypes
Abstract : We have used the chicken retina as a model for investigating cell cycle regulation and cell fate commitment during central nervous system development. This thesis focuses on the characterization of and commitment to the horizontal cell fate in the retina. READ MORE
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7. FLT3 receptor in normal and malignant hematopoiesis
Abstract : All hematopoietic cells originate from hematopoietic stem cells (HSCs) residing in the bone marrow (BM). The classical model of hematopoietic lineage commitment, that has been the prevailing model for hematopoiesis, proposes that the first lineage commitment step of HSCs and progenitors results in a strict separation of myelopoiesis and lymphopoiesis. READ MORE
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8. Cellular and Molecular Pathways Governing Hematopoietic Stem Cell Fate
Abstract : Hematopoietic Stem Cells (HSCs) have been defined to have abilities of both self-renewal and multi-lineage differen-tiation. The balance between these abilities is rigorously controlled under steady-state status (homeostasis) and when the normal processes of self-renewal and differentiation become deregulated, a disorder of blood system (such as leukemias) can occur. READ MORE
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9. Cytokine Regulation of Hematopoietic Stem Cells and Lymphopoiesis
Abstract : Large numbers of blood cells need to be continuously replaced in order to sustain the crucial functions of the immune system, oxygen transport and blood clotting. The large diversity of cell types required to maintain the integrity of the blood system are all produced from blood forming or hematopoietic stem cells (HSCs). READ MORE
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10. Not fully present : Five artworks by Maddie Leach
Abstract : This PhD by Prior Publications is a composition of five artistic projects by New Zealand artist Maddie Leach produced between 2008 and 2019. The text identifies persistent methodological tendencies in her artistic practice that combine an obstinate attachment to making something happen and willing cooperation with incompleteness, inconclusion, and variation. READ MORE