Search for dissertations about: "lineage"
Showing result 1 - 5 of 416 swedish dissertations containing the word lineage.
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1. Lineage commitment to a T
Abstract : he hematopoietic development is a highly dynamic but tightly regulated process. The flexibility to produce blood cells through more than one route will allow the blood system to respond rapidly in stress situations such as infections. READ MORE
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2. Molecular mechanisms in lymphoid restriction : securing the B lineage fate
Abstract : With the work in this thesis I have aimed to deepen the understanding of the mechanisms behind the development of different blood cell lineages with a specific focus on B cell development.To understand the interplay between extracellular signaling and transcription factor networks in early lymphoid development we investigated the functional collaborations of FLT3 and IL7R. READ MORE
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3. Cell lineage analysis in humans
Abstract : Delineating a cell’s history, where it came from and what has happened to it, can provide clues as to how tissues and organs are formed and function in the healthy state and in disease. The gold standard for tracing the relationships between cells and their progeny, is performed through prospective labeling with dyes or genetics tags. READ MORE
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4. Cellular pathways and molecular regulation of hematopoietic stem cells
Abstract : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. READ MORE
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5. Drivers of Population Dynamics in Bacterioplankton : Spotlight on Alphaproteobacteria and its dominant SAR11 Lineage
Abstract : Bacteria are mediators of biogeochemical cycles and are in this way vital for maintaining life on earth. Their distribution, abundance and functioning are driven by environmental heterogeneity and dynamic change in abiotic and biotic factors. READ MORE