Search for dissertations about: "linkage analysis"
Showing result 16 - 20 of 295 swedish dissertations containing the words linkage analysis.
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16. On the genetics of hereditary breast/ovarian cancer. BRCA1, BRCA2 and beyond
Abstract : Breast cancer is the most common malignancy in women. Most of the breast cancers are sporadic with no apparent inheritance factor but about 5-10% is believed to be caused by an inherited predisposition. Aims: This thesis aimed at defining the BRCA1/2 mutation spectrum of the west Swedish population and specifically to characterize the BRCA1c. READ MORE
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17. Linkage and association analysis in multiple sclerosis
Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that complex genetic factors influence susceptibility to MS. READ MORE
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18. Genetic and Molecular analysis of the Spinocerebellar ataxia type 7 (SCA7) disease gene
Abstract : Spinocerebellar ataxia type 7 (SCA7) is a hereditary neurodegenerative disorder affecting the cerebellum, pons and retina. SCA7 patients present with gait ataxia and visual impairment as the main symptoms. READ MORE
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19. Chicken Genomics - Linkage and QTL mapping
Abstract : This thesis presents results from genetic studies conducted in the chicken (Gallus gallus). The domestication of chicken is believed to have been initiated approximately 7,000 – 9,000 years ago in Southeast Asia. READ MORE
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20. Political Representation in the European Union : A Multi-Channel Approach
Abstract : The European Union (EU) is the most far-reaching attempt yet undertaken to institutionalize democratic policy-making beyond the nation-state. To what extent, and in what ways, do various channels of representation contribute towards the realization of this aim? This dissertation takes stock of current research on the EU’s system of representation, and seeks to expand its agenda so that this central question can be properly addressed. READ MORE