Search for dissertations about: "linkage and association analysis"
Showing result 1 - 5 of 123 swedish dissertations containing the words linkage and association analysis.
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1. Two Optimization Problems in Genetics : Multi-dimensional QTL Analysis and Haplotype Inference
Abstract : The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. READ MORE
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2. The population burden of gout and urate in Western Sweden : Prevalence, incidence, comorbidities, and association with cardiovascular disease
Abstract : Background: Gout is the most common type of inflammatory arthritis and is associated with several comorbidities and an increased risk of cardiovascular disease (CVD). However, data on the epidemiology and comorbidity patterns of gout in Sweden are scarce, and whether its association with CVD is causal or not, is not clear. READ MORE
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3. Genetic aspects of stroke : association and linkage studies in a northern Swedish population
Abstract : Stroke is a common, multifactorial cardiovascular disease. A stroke event is the result of traditional risk factors (i.e. hypertension, diabetes, smoking), environmental exposures and genetic factors in a complex interplay. READ MORE
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4. Exploring the Genetics of SLE with Linkage and Association Analysis
Abstract : The aim with this thesis has been to identify genes involved in the pathogenesis of Systemic Lupus Erythematosus (SLE). SLE is a systemic autoimmune disorder, most likely caused by both several genetic and environmental factors. READ MORE
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5. Genetic linkage and association studies in celiac disease: discoveries from whole genome analysis
Abstract : Celiac Disease (CD) or Gluten Sensitive Enteropathy (GSE) is a life-long disorder. It is characterized by inflammation in the small intestine of genetically predisposed individuals caused by inappropriate immune response to gluten, a protein enriched in some of our common grains (wheat, rye and barley). READ MORE