Search for dissertations about: "lipase B"

Showing result 16 - 20 of 73 swedish dissertations containing the words lipase B.

  2. 16. Lipase Specificity and Selectivity : Engineering, Kinetics and Applied Catalysis

    Author : Mohamad Takwa; Karl Hult; Bernhard Hauer; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi;

    Abstract : The specificity and selectivity of the enzyme Candida antarctica lipase B (CALB) were studiedfor several substrates and applications.With help of molecular modeling, the active site of CALB was redesigned for the ring openingpolymerization of D,D‐lactide. READ MORE

  4. 17. Enzymes as catalysts in synthesis of enantiomerically pure building blocks : secondary alcohols bearing two vicinal stereocenters

    Author : Rong Liu; Hans-Erik Högberg; Torbjörn Norin; Thorleif Anthonsen; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzyme; kinetic resolution; enantioselectivity; lipase; diastereoselectivity; epimerisation; metal-catalysed transformation; intramolecular alkylation.; Chemistry; Kemi;

    Abstract : Enzymes as tools in organic synthesis have provided enormous advantages. This thesis deals with the applications of enzymes in the kinetic resolutions of racemic compounds. The stereochemistry of chiral compounds and the kinetics of α/β hydrolase lipases are presented. READ MORE

  5. 18. Building blocks for polymer synthesis by enzymatic catalysis

    Author : Stefan Semlitsch; Mats Martinelle; Sergio Riva; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Enzyme; Enzyme Engineering; Biocatalysis; Lipase; CalB; MsAcT; Substrate specificity; Selectivity; Polymer Chemistry; Polymer Synthesis; Bioteknologi; Biotechnology;

    Abstract : The search for alternatives to oil-based monomers has sparked interest for scientists to focus on the use of renewable resources for energy production, for the synthesis of polymeric materials and in other areas. With the use of renewable resources, scientists face new challenges to first isolate interesting molecules and then to process them. READ MORE

  6. 19. Enantioselective biotransformations using engineered lipases from Candida antarctica

    Author : Karin Engström; Jan-E. Bäckvall; Manfred T. Reetz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein engineering; directed evolution; kinetic resolution; dynamic kinetic resolution; biotransformation; lipase; organisk kemi; Organic Chemistry;

    Abstract : Enzymes are attractive catalysts in organic synthesis since they are efficient, selective and environmentally friendly. A large number of enzyme-catalyzed transformations have been described in the literature. READ MORE

  7. 20. Enzyme substrate solvent interactions : a case study on serine hydrolases

    Author : Linda Fransson; Karl Hult; Jürgen Pleiss; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lipase; esterase; specificity; Bioengineering; Bioteknik;

    Abstract : Reaction rates and selectivities were measured for transacylation of fatty acid esters in solvents catalysed by Candida antarctica lipase B and by cutinase from Humicola insolens. With these enzymes classical water-based enzymology can be expanded to many different solvents allowing large variations in interaction energies between the enzymes, the substrates and the surrounding. READ MORE