Search for dissertations about: "lipase from pseudomonas"

Showing result 1 - 5 of 10 swedish dissertations containing the words lipase from pseudomonas.

  1. 1. Chiral building blocks for synthesis of pine sawfly sex pheromones Enantioselective Lipase Catalysed Acylations and Esterifications of Primary Alcohols and Acids and Synthesis of the Sex Pheromone of the Pine Sawfly Microdiprion pallipes

    Author : Ba-Vu Nguyen; KTH; []
    Keywords : lipase; Pseudomonas cepacia; Candida rugosa; enantioselective; enantiomeric ratio; primary 2-methylalcohol; substituted-methylcarboxylic acid; pine sawfly; Microdiprion pallipes; sex pheromone; 3; 7; 11-trimethyl-2-tridecanol; stereoisomer;

    Abstract : This thesis describes the development of new methods for thepreparation of enantiomerically pure methyl branched alkylcompounds and their use as building blocks in the synthesis ofstereoisomerically pure pheromones of pine sawflies.The high regioselectivity, enantioselectivity and activityof lipases in organic solvent in conjunction withenvironmentally compatible reaction conditions have madelipase-catalysed synthesis an attractive alternative toconventional synthetic methods in organic chemistry. READ MORE

  2. 2. Enzymes as catalysts in synthesis of enantiomerically pure building blocks : secondary alcohols bearing two vicinal stereocenters

    Author : Rong Liu; Hans-Erik Högberg; Torbjörn Norin; Thorleif Anthonsen; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzyme; kinetic resolution; enantioselectivity; lipase; diastereoselectivity; epimerisation; metal-catalysed transformation; intramolecular alkylation.; Chemistry; Kemi;

    Abstract : Enzymes as tools in organic synthesis have provided enormous advantages. This thesis deals with the applications of enzymes in the kinetic resolutions of racemic compounds. The stereochemistry of chiral compounds and the kinetics of α/β hydrolase lipases are presented. READ MORE

  3. 3. Transition metal- and lipase-catalyzed reactions : Dynamic resolutions, hydrogen transfer and enzyme engineering

    Author : Patrik Krumlinde; Jan-Erling Bäckvall; Johannes G. de Vries; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dynamic kinetic resolution; dynamic kinetic asymmetric transformation; hydrogen transfer; directed evolution; enzyme engineering; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis mainly focuses on chemoenzymatic processes and can be divided into three parts: The first part of the thesis, chapters 2-4, is devoted to the development of combined ruthenium- and enzyme-catalyzed dynamic processes. In these processes the metal catalyst racemizes (epimerizes) the alcohol substrate via hydrogen transfer and the enzyme transforms the substrate into enantiomerically enriched product. READ MORE

  4. 4. Towards sustainable plastics : Microbial production of aromatic and aliphatic building blocks from biobased feedstock and plastic hydrolysate

    Author : Oliver Englund Örn; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cell factories; Biobased plastics; Protocatechuic acid; Adipic acid; 4-Hydroxybyratate; 1; 4-Butanediol; PBAT; Enzymatic recycling; Synthetic promoter library;

    Abstract : The current plastic system is unsustainable and needs to change. Plastics are mainly produced from fossil feedstock, contributing to greenhouse gas emissions, and low rate of post-consumer recycling results in pollution on land and in oceans with high ecological impact, and huge loss of valuable material. READ MORE

  5. 5. Synthesis of Molecular Probes for Exploring the Human Consciousness, 5-HT7 Ligands and Salvinorins

    Author : Pär Holmberg; Anders Karlén; Adolf Gogoll; Anette Johansson; Christer Sahlberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; serotonin system; opioid system; selective 5-HT7 agonist; 3-aminchromans; salvinorin A; selective kappa opioid receptor; mental disorders; consciousness; regioselective oxidation; enzymatic kinetic resolution; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Abstract : In this study, we have addressed the serotonergic and the opioid system within the CNS. Both systems are of outmost importance in the etiology of disease states, especially mental disorders. READ MORE