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Showing result 1 - 5 of 60 swedish dissertations matching the above criteria.

2. 1. Tethered Lipid Vesicles as Nanoscale Sensor Elements

   Author : Seyed Tabaei; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aquaglyceroporin; lipid vesicles; total internal reflection fluorescence TIRF microscopy; cell membrane; aquaporin; pore formation; surface plasmon resonance SPR ; phospholipase A2; antiviral peptide; lipid bilayer; biosensing; microfluidics;

   Abstract : The primary aim of this thesis work has been to explore and advance the potential of surface tethered lipid vesicles as a platform for studying in particular the following three biomembrane-related processes: trans-membrane transport, membrane-peptide interactions and the activity of membrane active enzymes. First, a method based on surface plasmon resonance (SPR) spectroscopy was developed for studying passive diffusion processes as well as the membrane-protein mediated transport of small non electrolyte molecules across lipid bilayers. READ MORE

4. 2. Membrane-Polymer Interactions in Lipid Vesicles

   Author : Ilona Wegrzyn; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; lipid nanotube; liposome; multifunctional pipette; PNIPAAm; lipid bilayer; giant unilamellar vesicle;

   Abstract : Membrane related biological processes are commonly investigated in artificial biomimetic experimental systems. One of the most versatile models is based upon giant unilamellar phospholipid vesicles (liposomes), which are artificially generated spherical lipid structures in an aqueous environment. READ MORE

5. 3. Mesoporous supported lipid bilayers

   Author : Maria Claesson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; FRAP; Lipid bilayer; Mesoporous; AFM; Vesicle; Titania; Silica; QCM-D;

   Abstract : AbstractLipid bilayers are commonly used as simplified model systems of living cell membranes. They have shown to be important components in the development of biosensing devices where the bilayer acts as a host for transmembrane proteins, such as ion channels, that are utilized as sensing elements. READ MORE

6. 4. Formation of Mesoporous Materials and their use as Lipid Bilayer Supports

   Author : Maria Wallin; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; tethered lipid bilayers; meso-ordered PEG-DA hydrogels; dendrimers; porous silica and titania; lipid bilayers; biosensing;

   Abstract : Mesoporous materials have acquired great scientific interest in various applications; something that is largely due to that their properties, such as pore size, pore orientation, material composition and surface chemistry, can be controlled to a large extent. One idea, which has been investigated in this thesis, is to use mesoporous materials as supports for lipid bilayers and by doing so fabricate devices that mimic the cell wall and at the same time has sufficient mechanical robustness for practical use. READ MORE

7. 5. Nanosized Bilayer Disks as Model Membranes for Interaction Studies

   Author : Anna Lundquist; Katarina Edwards; Marja-Liisa Riekkola; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Disk; disc; lipid bilayer; PEG-lipid; model membrane; interaction; partitioning; drug; liposome; cryo-TEM; neutron scattering; capillary electrophoresis; immobilization; biosensor; membrane protein; melittin; Chemistry; Kemi;

   Abstract : PEG-lipid stabilized bilayer disks have been found in lipid mixtures containing polyethylene glycol (PEG)-lipids where the combination of a high bending rigidity and low PEG-lipid/lipid miscibility favours disk formation. The disks are planar and circular in shape and their long-term stability is excellent. READ MORE