Search for dissertations about: "lipid droplet"
Showing result 1 - 5 of 29 swedish dissertations containing the words lipid droplet.
-
1. Cardiac lipid storage and metabolism following myocardial ischemia
Abstract : Myocardial ischemia is associated with cellular- and metabolic adjustments within the heart, including accumulation of lipids. Myocardial lipids are stored in cytosolic droplets, consisting of a core of neutral lipids surrounded by a complex surface containing proteins, such as perilipins. READ MORE
-
2. Engineering Lipid Metabolism for Production of Oleochemicals in Saccharomyces cerevisiae
Abstract : Oleochemicals are chemicals usually derived from plant oils or animal fat. Large use of plant oil derivatives as replacements for petroleum-derived chemicals brings sustainability issues from extensive cultivation of oil plants in restricted regions. READ MORE
-
3. The assembly of cytosolic lipid droplets and its effect on insulin sensitivity
Abstract : Accumulation of neutral lipids, in particular triglycerides, in non-adipocytes is highly related to the development of insulin resistance and its consequences, type-2 diabetes and cardiovascular diseases. The accumulation of triglycerides occurs in so-called lipid droplets in the cytosol. READ MORE
-
4. Lipid storage and secretion. Studies on VLDL assembly and foam cell formation
Abstract : This thesis deals with formation of two factors of upmost importance for the development of atherosclerosis: the triglyceride rich very low density lipoproteins 1 (VLDL1) and the lipid loaded macrophages ("foam cells"- characteristic features of the atherosclerotic lesion). Both these processes depend on the cellular accumulation of lipids. READ MORE
-
5. Intracellular lipids and inflammatory activity in macrophage foam cells
Abstract : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. READ MORE