Search for dissertations about: "lipid lowering"

Showing result 1 - 5 of 93 swedish dissertations containing the words lipid lowering.

  2. 1. Mechanisms behind the lipid-lowering effects of ACTH - Studies in different experimental models

    Author : Maria Skoog; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Lipid; ACTH; Apolipoprotein-B; Cholesterol; Human; Rat; Rabbit; Medicin människa och djur ;

    Abstract : Abstract Adrenocorticotrophic hormone (ACTH) has strong and direct lipid-lowering effects in man. All apoB-containing lipoproteins, i.e. VLDL, LDL, Lp(a), are reduced by 25-30%. READ MORE

  4. 2. Adherence to lipid-lowering medications and cardiovascular disease prevention in type 2 diabetes mellitus

    Author : Sofia A. Karlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medication adherence; refill adherence; medication persistence; pharmacoepidemiology; lipid-lowering medications; type 2 diabetes mellitus; cardiovasular disease; all-cause mortality; cardiovascular mortality; guideline adherence;

    Abstract : Background and aims: Globally, cardiovascular disease (CVD) is the major cause of death among patients with type 2 diabetes mellitus (T2DM). Improved control of LDL cholesterol with lipid-lowering medications and patients’ adherence to such medications have been shown associate with lower risk of CV events and mortality among T2DM patients. READ MORE

  5. 3. Studies on antioxidant and lipid lowering effects on human microcirculation

    Author : Qing Lu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Microcirculation; oxidative stress; antioxidant; smoking. hypercholesterolemia; diabetes; vitamin C; Nacetylcysteine; lipid lowering; capillary blood flow velocity; post reactive hyperemia; endothelial function.;

    Abstract : In previous work from this laboratory, vital microscopy was successfully used to study rnicrocirculatcry effects of hypercholesterolemia in a rabbit model. Hypercholesterolemia caused a dramatic depression of the blood flow velocity in the conjunctiva microvessels of the rabbits. READ MORE

  6. 4. Platelet function in hyperlipoproteinemia and effects of lipid-lowering treatment

    Author : Anders Bröijersén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Coronary atherosclerosis and thrombus formation on fissuring atherosclerotic plaques are key events in the development of coronary artery disease. Hyperlipoproteinemia induces atherosclerosis but may also exert direct prothrombotic effects via platelet activation. READ MORE

  7. 5. Pharmacoepidemiologic studies on cardiovascular drugs - with special reference to the effectiveness and safety of blood pressure lowering drugs

    Author : Juan Merlo; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; samhällsmedicin; Socialmedicin; cardiovascular epidemiology; Pharmacoepidemiology; blood pressure; hypertension; cardiovascular drugs; antihypertensive drugs; lipid lowering drugs; nitrates; effectiveness; safety; ecologic studies; Social medicine; cohort studies; farmakognosi; farmaci; toxikologi;

    Abstract : Background: Ischaemic heart disease (IHD) and stroke are the main causes of morbidity and mortality in developed countries and hence constitute a large public health problem. Cardiovascular drugs are used in an effort to prevent (e. g. blood pressure lowering drugs (BPLD) and lipid lowering drugs) and palliate (e. READ MORE