Search for dissertations about: "lipid vesicles"

Showing result 1 - 5 of 145 swedish dissertations containing the words lipid vesicles.

2. 1. Tethered Lipid Vesicles as Nanoscale Sensor Elements

   Author : Seyed Tabaei; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aquaglyceroporin; lipid vesicles; total internal reflection fluorescence TIRF microscopy; cell membrane; aquaporin; pore formation; surface plasmon resonance SPR ; phospholipase A2; antiviral peptide; lipid bilayer; biosensing; microfluidics;

   Abstract : The primary aim of this thesis work has been to explore and advance the potential of surface tethered lipid vesicles as a platform for studying in particular the following three biomembrane-related processes: trans-membrane transport, membrane-peptide interactions and the activity of membrane active enzymes. First, a method based on surface plasmon resonance (SPR) spectroscopy was developed for studying passive diffusion processes as well as the membrane-protein mediated transport of small non electrolyte molecules across lipid bilayers. READ MORE

4. 2. Formation of Block Copolymer and Surfactant Vesicles

   Author : Karin Bryskhe; Fysikalisk kemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Polymerteknik; Fysikalisk kemi; biopolymers; Polymer technology; nanoparticles; Lipid; triblock copolymer; surfactants; Nonionic; Vesicles; Formation; Physical chemistry;

   Abstract : In this thesis temperature induced vesicle formation in both a block copolymer system and nonionic surfactant system have been investigated. The block copolymer is a triblock copolymer of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), PEO-PPO-PEO, with the average molecular composition of EO5PO68EO5 and the commercial trade name Pluronic L121 (papers I, II). READ MORE

5. 3. Membrane-Polymer Interactions in Lipid Vesicles

   Author : Ilona Wegrzyn; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; lipid nanotube; liposome; multifunctional pipette; PNIPAAm; lipid bilayer; giant unilamellar vesicle;

   Abstract : Membrane related biological processes are commonly investigated in artificial biomimetic experimental systems. One of the most versatile models is based upon giant unilamellar phospholipid vesicles (liposomes), which are artificially generated spherical lipid structures in an aqueous environment. READ MORE

6. 4. DNA-Controlled Lipid-Membrane Fusion

   Author : Lisa Simonsson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; exocytosis; vesicles; DNA; FRET; fluorescence resonance energy transfer; model system; total internal reflection fluorescence microscopy; TIRF microscopy; self-assembly; site-specificity; diffusion; biomembranes; lipid bilayer; membrane fusion;

   Abstract : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. We have demonstrated that short DNA oligonucleotides, membrane-attached via CH in an orientation that mimics the overall zipperlike architecture of fusion-inducing proteins, induce fusion of both suspended vesicles and vesicles site-specifically tethered to SLBs. READ MORE

7. 5. Lipid Vesicle Fusion: Investigation, Generation and Manipulation of Cell-Membrane Mimics

   Author : Lisa Simonsson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; diffusion; spreading lipid bilayers; cell mimic; micromanipulation; lipid bilayer; microfluidics; site-specificity; DNA; membrane-receptor interactions; total internal reflection fluorescence microscopy; model system; self-assembly; TIRF microscopy; FRET; exocytosis; vesicles; fluorescence resonance energy transfer; biomembranes; amperometry; membrane fusion;

   Abstract : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. In this work, cell-membrane mimics were constructed and evaluated as models for studies of the membrane-fusion process. READ MORE