Search for dissertations about: "lipidomics"

Showing result 1 - 5 of 9 swedish dissertations containing the word lipidomics.

  1. 1. Studies of atherogenic lipoproteins using mass spectrometry-based lipidomics

    Author : Marcus Ståhlman; Göteborgs universitet.; Gothenburg University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipids; lipoproteins; atherogenesis; lipidomics; type 2 diabetes; mass spectrometry;

    Abstract : The prevalence of type 2 diabetes is increasing worldwide and is about to reach epidemic proportions. The disease is often associated with dyslipidemia which is characterized by an atherogenic lipoprotein profile including elevated serum triacylglycerol levels, low high-density lipoprotein levels and high levels of small low-density lipoproteins. READ MORE

  2. 2. Imaging mass spectrometry for in situ lipidomics: from cell structures to cardiac tissue

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Sanna Sämfors; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Myocardial infarction; PC12 cells; Cell membrane; Mass spectrometry imaging; Sample preparation; Lipidomics; ToF-SIMS; Gas cluster ion beam;

    Abstract : Imaging of cells and tissues is important for studying different processes within biological systems due to the spatial information provided for different molecular species during imaging. One powerful imaging technique is mass spectrometry imaging (MSI). READ MORE

  3. 3. Development of Enhanced Analytical Methodology for Lipid Analysis from Sampling to Detection A Targeted Lipidomics Approach

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Giorgis Isaac; Uppsala universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; electrospray ionization; lipids; liquid chromatography; mass spectrometry; pesticides; phosphatidylcholine; pressurized fluid extraction; sphingomyelin; sulfatides; Analytisk kemi; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Abstract : This thesis covers a wide range of analytical method development for lipid analysis in complex biological samples; from sample preparation using pressurized fluid extraction (PFE) and separation with reversed phase capillary liquid chromatography (RP-LC) to detection by electrospray ionization mass spectrometry (ESI/MS) and tandem MS.The requirements for fast, reliable and selective extraction methods with minimal usage of solvents have accelerated the development of new extraction techniques. READ MORE

  4. 4. A functional genomic investigation of an alternative life history strategy The Alba polymorphism in Colias croceus

    University dissertation from Stockholm : Department of Zoology, Stockholm University

    Author : Alyssa Woronik; Stockholms universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; alternative life history strategy; butterfly wing color; Alba; Colias; color polymorphism; dimorphism; life history traits; physiology; lipidomics; genomics; pooled sequencing; phylogenomics; RNA-Seq; Pool-Seq; populationsgenetik; Population Genetics;

    Abstract : Life history traits affect the timing and pattern of maturation, reproduction, and survival during an organism’s lifecycle and are the major components influencing Darwinian fitness. Co-evolved patterns of these traits are known as life history strategies (LHS) and variation occurs between individuals, populations, and species. READ MORE

  5. 5. Applications of nanospray desorption electrospray ionization mass spectrometry In situ lipid and metabolite analysis from cells to tissue

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hilde-Marléne Bergman; Uppsala universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; mass spectrometry imaging MSI ; nanospray desorption electrospray ionization nano-DESI ; single-cell analysis; neurotransmitter imaging; diabetic nephropathy; pneumatic nebulization; lipidomics; metabolomics; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : Ambient mass spectrometry (MS) has proved to be an important addition to the bioanalytical toolbox. These methods perform analyte sampling and ionization under atmospheric pressure, and require very little sample preparation other than the sampling process in front of the machine. READ MORE