Search for dissertations about: "lipopolysaccharide"

Showing result 1 - 5 of 208 swedish dissertations containing the word lipopolysaccharide.

  1. 1. Vascular actions of antimicrobial peptides

    University dissertation from Cristina Ciornei, [email protected], Department of Anaesthesiology and Intensive Care, Lund Univerity Hospital, Lund, Sweden

    Author : Cristina Ciornei; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; vascular smooth muscle; sepsis; nitric oxide; human antimicrobial peptide LL-37; Antimicrobial peptides; lipopolysaccharide; bactericidal permeability-increasing protein;

    Abstract : The present thesis focuses on the vascular effects of antimicrobial peptides especially mechanisms involving the vasodilator nitric oxide (NO), which is released from the blood vessel wall during inflammatory conditions such as sepsis. Bacterial lipopolysaccharide stimulates the expression of nitric oxide synthase (iNOS), which increases the NO production in vascular tissues or cultured vascular smooth muscle cells (VSMC). READ MORE

  2. 2. Studies of the pathogenesis of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura

    University dissertation from Department of Pediatrics, Lund University

    Author : Diana Karpman; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatri; Pediatrics; tumor necrosis factor; interleukin 6; von Willebrand factor; apoptosis; lipopolysaccharide; shiga-like toxin; Escherichia coli O157:H7; Hemolytic uremic syndrome; thrombotic thrombocytopenic purpura; Urology; nephrology; Urologi; nefrologi;

    Abstract : This study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. READ MORE

  3. 3. Modulating Organ Dysfunction in Experimental Septic Shock Effects of Aminoglycosides, Antiendotoxin Measures and Endotoxin Tolerance

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Markus Castegren; Jan Sjölin; Claes Frostell; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipopolysaccharide; animal model; pig; tobramycin; endotoxin elimination; immunoparalysis; secondary sepsis; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

    Abstract : Sepsis is a common diagnose in the intensive care population, burdened with a high mortality. The systemic inflammatory reaction underlying the development of septic organ dysfunction can be modeled using Gram-negative bacterial lipopolysaccharide, endotoxin. READ MORE

  4. 4. Physiology of Escherichia coli in batch and fed-batch cultures with special emphasis on amino acid and glucose metabolism

    University dissertation from Stockholm : Bioteknologi

    Author : Ling Han; [2002]
    Keywords : escherichia coli; amino acids; glycine; quorum sensing; metabolic switch; metabolite po9ols; carbon balance; outer membrne; lipopolysaccharide; batch culture;

    Abstract : The objective of this work is to better understand themetabolism and physiology ofEscherichiacoli(W3110) in defined medium cultures with thelong-term goal of improving cell yield and recombinant proteinproductivity.The order of amino acid utilization inE. colibatch cultures was investigated in a medium with16 amino acids and glucose. READ MORE


    University dissertation from Department of Clinical Sciences, Lund University

    Author : Jakob B Axelsson; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nuclear factor kappa B; neutrophils; monocytes; acute pancreatitis; ductal cells; active site-inhibited factor seven; heparan sulfate; lipopolysaccharide; innate immune response;

    Abstract : Heparan sulfate (HS), a substance common in the extracellular matrix on epithelial cells is present in the pancreas, lining the duct lumen. During pathological conditions, we propose that it can be shed from the ECM and bind to receptors on the cell surface, thus triggering an inflammatory response, which if excessive can cause acute pancreatitis (AP). READ MORE