Search for dissertations about: "lipopolysaccharide"

Showing result 16 - 20 of 222 swedish dissertations containing the word lipopolysaccharide.

  2. 16. Structural Studies of O-Polysaccharides from Diarrhoeal Escherichia coli

    Author : Tara Ali; Göran Widmalm; Andrej Weintraub; Lennart Kenne; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; Lipopolysaccharide; NMR; biological repeating unit; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : This thesis describes the structural analysis of O-polysaccharides from the Gram-negative bacterium Escherichia coli that is a diarrhoeal pathogen. The Escherichia coli serotypes investigated were O178, O171, O166 and O128. The methods used in these studies were nuclear magnetic resonance spectroscopy and component analysis. READ MORE

  4. 17. Aspects on sepsis : treatment and markers

    Author : Anna Gustafsson; Malmö högskola; []
    Keywords : antimicrobial peptides; cytokines; lipoteichoic acid; lipopolysaccharide; soluble urokinase plasminogen activator receptor; sepsis;

    Abstract : Sepsis is one of the greatest challenges in critical care medicine today, while the treatment of sepsis and evaluation of its severity is complicated. The first part of this thesis presents two approaches on the use of antimicrobial peptides in sepsis treatment, relying on both soluble and immobilized peptides. READ MORE

  5. 18. Taming the Griffin : Membrane interactions of peripheral and monotopic glycosyltransferases and dynamics of bacterial and plant lipids in bicelles

    Author : Jobst Liebau; Lena Mäler; Charles Sanders; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane; bicelle; lipid; detergent; lipopolysaccharide; glycosyltransferase; WaaG; fluorescence; circular dichroism; NMR; paramagnetic relaxation enhancement; model-free approach; dynamics; Biophysics; biofysik;

    Abstract : Biological membranes form a protective barrier around cells and cellular compartments. A broad range of biochemical processes occur in or at membranes demonstrating that they are not only of structural but also of functional importance. One important class of membrane proteins are membrane-associated glycosyltransferases. READ MORE

  6. 19. Antibiotic uptake in Gram-negative bacteria

    Author : Claudio Muheim; Daniel Daley; Jean-Marie Pagès; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gram-negative bacteria; Antibiotic uptake; Outer membrane; Lipopolysaccharide; Biochemistry; biokemi;

    Abstract : The increasing emergence and spread of antibiotic-resistant bacteria is a serious threat to public health. Of particular concern are Gram-negative bacteria such as Escherichia coli, Acinetobacter baumannii, Klebsiella pneumoniae or Pseudomonas aeruginosa. READ MORE

  7. 20. Structural Studies of O-antigen polysaccharides, Synthesis of 13C-labelled Oligosaccharides and Conformational Analysis thereof, using NMR Spectroscopy

    Author : Ulrika Olsson; Göran Widmalm; Corine Sandström; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; conformation; Escherichia coli; lipopolysaccharide; O-antigen; carbohydrates; structure; isotopic labelling; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : In order to understand biological processes, to treat and diagnose diseases, find appropriate vaccines and to prevent the outbreak of epidemics, it is essential to obtain more knowledge about carbohydrate structures. This thesis deals with structure and conformation of carbohydrates, analysed by NMR spectroscopy and MD simulations. READ MORE