Search for dissertations about: "lipoprotein a"

Showing result 1 - 5 of 305 swedish dissertations containing the words lipoprotein a.

  2. 1. Lipoprotein(a) in cardiovascular disease

    Author : Ulf Lundstam; Göteborgs universitet; []
    Keywords : atherosclerosis; Lipoprotein a ; LDL; extracellular matrix; women;

    Abstract : The atherosclerotic process is continuous and starts early in life. Risk factors for atherosclerosis include hyperlipidemia, hypertension, smoking and diabetes mellitus. Fatty streaks characterised by lipid-laden macrophages are early signs of atherosclerosis. READ MORE

  4. 2. Biophysical Studies of Apolipoprotein A-IM and a Partitioning study

    Author : Malin Suurkuusk; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Apolipoprotein A-IMilano; Apolipoprotein A-I; Lipoprotein; Lipid; Microcalorimetry; DCS; Denaturation; Guanidine Hydrochloride; Physics; Fysik; Chemistry; Kemi;

    Abstract : The major part of this thesis deals with the similarities and differences in some biophysical properties of apolipoprotein A-I (apo A-I) and the molecular variant apolipoprotein A-IMilano (apo A-IM), and the influence on lipid binding. A model compound partitioning study has also been performed. READ MORE

  5. 3. Lipoprotein lipase : mechanism for adaptation of activity to the nutritional state

    Author : Gengshu Wu; Thomas Olivecrona; Gunilla Olivecrona; Peter Nisson-Ehle; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; adipose tissue; heparin; extracellular; nutrition; turnover; actinomycin; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Lipoprotein lipase (LPL) is an enzyme to hydrolyze triglycerides in lipoproteins and thereby make the fatty acids available for cellular metabolic reactions. Short-term fasting down-regulates LPL activity in adipose tissue. This regulation is through post-translational mechanism. READ MORE

  6. 4. The interplay between lipoproteins, immunity and tryptophan metabolism in atherosclerosis

    Author : Konstantinos A Polyzos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Atherosclerotic cardiovascular disease (CVD) is the leading cause of mortality worldwide. Atherosclerosis is initiated by the infiltration and accumulation of low-density lipoprotein (LDL) cholesterol in the vascular wall, which activates the innate and adaptive arm of immunity, thereby causing chronic vascular inflammation. READ MORE

  7. 5. Regulation of Lipoprotein Lipase Activity : an In-vitro Study of a Complex and Dynamic System

    Author : Oleg Kovrov; Gunilla Olivecrona; Aivar Lookene; Mikael Larsson; Geesje Dallinga-Thie; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Triglyceride Metabolism; Lipoprotein lipase; Angiopoietin-Like Proteins; Apolipoproteins; Isothermal titration calorimetry; Biochemistry; biokemi; molekylärbiologi; Molecular Biology;

    Abstract : The progress of human society outpaces our biological evolution, and this brings unexpected health problems. The industrial revolution brought up dramatic changes in nutrition and lifestyle – we are increasingly shifting towards a nutrient-rich Western-patterned diet and to a sedentary lifestyle. READ MORE