Search for dissertations about: "lipoteichoic acid"

Found 5 swedish dissertations containing the words lipoteichoic acid.

  2. 1. Aspects on sepsis : treatment and markers

    Author : Anna Gustafsson; Malmö högskola; []
    Keywords : antimicrobial peptides; cytokines; lipoteichoic acid; lipopolysaccharide; soluble urokinase plasminogen activator receptor; sepsis;

    Abstract : Sepsis is one of the greatest challenges in critical care medicine today, while the treatment of sepsis and evaluation of its severity is complicated. The first part of this thesis presents two approaches on the use of antimicrobial peptides in sepsis treatment, relying on both soluble and immobilized peptides. READ MORE

  4. 2. Actions of Antimicrobial Peptides and Bacterial Components in Inflammation

    Author : Thorgerdur Sigurdardottir; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; LL-37; M1 protein; S. pyogenes; Toll-like receptors; phenylephrine; nitr1c oxide; antimicrobial peptides;

    Abstract : Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response contributing to septic shock. READ MORE

  5. 3. Toll-like receptor-induced cytokine secretion by human monocytes in healthy donors and septic patients assessed at the single cell level

    Author : Christian Smedman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Following the ligation of Toll-like receptors (TLRs) by bacterial-derived signature molecules, innate immune cells such as monocytes, macrophages and neutrophils initiate the inflammatory process by secreting chemokines and cytokines with a wide range of immunomodulatory effects. Under normal conditions, these mediators work to compartmentalize the inflammatory process and eradicate the intruder, while simultaneously recruiting more immune cells to the site of infection. READ MORE

  6. 4. The role of nitric oxide in porcine models of asthma and acute lung injury

    Author : Roelinde Middelveld; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nitric oxide (NO) is a modulator of many important physiological processes in the body. It is produced endogenously in several cell types by a family of NO synthases (NOS). READ MORE

  7. 5. Role of macrophage receptor MARCO in host defense

    Author : Marko Sankala; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MARCO; innate immunity; scavenger receptor.;

    Abstract : Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during infection. READ MORE