Search for dissertations about: "liquid chromatography mass spectrometry"

Showing result 1 - 5 of 268 swedish dissertations containing the words liquid chromatography mass spectrometry.

  2. 1. Liquid Chromatography Coupled to Mass Spectrometry : Implementation of Chemometric Optimization and Selected Applications

    Author : My Moberg; Jonas Bergquist; Karin E. Markides; Dan Bylund; Douglas B. Kell; Uppsala universitet; []
    Keywords : Analytical chemistry; liquid chromatography; mass spectrometry; tandem mass spectrometry; electrospray ionization; inductively coupled plasma; chemometrics; optimization; multivariate data analysis; design of experiments; response surface model; siderophore; azathioprine; peptide; Analytisk kemi;

    Abstract : Liquid chromatography (LC) coupled to mass spectrometry (MS) offers highly selective and sensitive analysis of a wide variety of compounds. However, the use of hyphenated experimental set-ups implies that many parameters may have an effect on the studied response. READ MORE

  4. 2. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

    Author : Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. READ MORE

  5. 3. Metabolic Studies with Liquid Separation Coupled to Mass Spectrometry

    Author : Erik Allard; Jonas Berguist; Per Sjöberg; Risto Kostiainen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; liquid chromatography; mass spectrometry; tandem mass spectrometry; method development; capillary electrophoresis; electrospray ionization; time-of-flight; quantitation; metabolomics; metabonomics; pattern recognition; ximelagatran; melagatran; charge state; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : Metabolism is the sum of all chemical processes with the purpose to maintain life, as well as enable reproduction, in a living organism. Through the study of metabolism, increased understanding of pharmacological mechanisms and diseases can be achieved. READ MORE

  6. 4. Chemometric tools for enhanced performance in liquid chromatography-mass spectrometry

    Author : Dan Bylund; Mittuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chemometrics; liquid chromatography; mass spectrometry; Chemistry; Kemi; MATHEMATICS; MATEMATIK; Analytical Chemistry;

    Abstract : .... READ MORE

  7. 5. Efficient algorithms for highly automated evaluation of liquid chromatography - mass spectrometry data

    Author : Mattias Fredriksson; Dan Bylund; Patrik Petersson; Bengt-Olof Axelsson; Mittuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Digital filtering; Liquid chromatography; Mass spectrometry; Method; Chemistry; Kemi;

    Abstract : Liquid chromatography coupled to mass spectrometry (LC‐MS) has due to its superiorresolving capabilities become one of the most common analytical instruments fordetermining the constituents in an unknown sample. Each type of sample requires a specificset‐up of the instrument parameters, a procedure referred to as method development. READ MORE