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Showing result 1 - 5 of 90 swedish dissertations matching the above criteria.

2. 1. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

   Author : Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

   Abstract : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. READ MORE

4. 2. Liquid Chromatography – Mass Spectrometry Analysis of Short-lived Tracers in Biological Matrices : Exploration of Radiotracer Chemistry as an Analytical Tool

   Author : Martin Lavén; Karin Markides; Bengt Långström; Rolf Ekman; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; liquid chromatography - mass spectrometry; radiotracer chemistry; positron emission tomography; biological samples; radionuclide imaging; Analytisk kemi; Analytical chemistry; Analytisk kemi;

   Abstract : Liquid chromatography – mass spectrometry (LC-MS) methods were developed for the analysis of positron emission tomography (PET) radiotracers in biological matrices. Additionally, radiotracer chemistry was explored as an analytical tool for supporting LC-MS method development and imaging molecular interactions in miniaturised chemical analysis systems. READ MORE

5. 3. Chemometric tools for enhanced performance in liquid chromatography-mass spectrometry

   Author : Dan Bylund; Mittuniversitetet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chemometrics; liquid chromatography; mass spectrometry; Chemistry; Kemi; MATHEMATICS; MATEMATIK; Analytical Chemistry;

   Abstract : .... READ MORE

6. 4. Efficient algorithms for highly automated evaluation of liquid chromatography - mass spectrometry data

   Author : Mattias Fredriksson; Dan Bylund; Patrik Petersson; Bengt-Olof Axelsson; Mittuniversitetet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Digital filtering; Liquid chromatography; Mass spectrometry; Method; Chemistry; Kemi;

   Abstract : Liquid chromatography coupled to mass spectrometry (LC‐MS) has due to its superiorresolving capabilities become one of the most common analytical instruments fordetermining the constituents in an unknown sample. Each type of sample requires a specificset‐up of the instrument parameters, a procedure referred to as method development. READ MORE

7. 5. Liquid chromatography : mass spectrometry study of two biochemical alcohol markers

   Author : Niclas Nikolai Stephanson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The interest in biochemical alcohol markers for detecting acute and chronic alcohol consumption has expanded greatly during recent years. The development and application of laboratory tests identifying early problematic drinking and monitoring abstinence have the potential of reducing the healthcare costs and suffering associated with alcohol misuse. READ MORE