Search for dissertations about: "liquid chromatography-mass spectrometry"

Showing result 16 - 20 of 90 swedish dissertations containing the words liquid chromatography-mass spectrometry.

  2. 16. Algorithms and Methods for Robust Processing and Analysis of Mass Spectrometry Data

    Author : Jonatan Eriksson; Avdelningen för Biomedicinsk teknik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Algorithms; Signal Processing; Dynamic Programming; Biomarker discovery; High-dimensional data;

    Abstract : Liquid chromatography-mass spectrometry (LC-MS) and mass spectrometry imaging (MSI) are two techniques that are routinely used to study proteins, peptides, and metabolites at a large scale. Thousands of biological compounds can be identified and quantified in a single experiment with LC-MS, but many studies fail to convert this data to a better understanding of disease biology. READ MORE

  4. 17. Development of Techniques and Methods for the Quantitative Analysis of Endogenous Substances by Microcolumn Liquid Chromatography Coupled to Mass Spectrometry

    Author : Ardeshir Amirkhani; Jonas Bergquist; Karin E. Markides; Fritz Erni; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Abstract : Liquid chromatography-mass spectrometry (LC-MS) is a powerful technique for the analysis of endogenous compounds. The introduction of electrospray ionization (ESI) as an interface between LC and MS has contributed strongly to a trend towards miniaturization of LC, due to the possibility to perform ESI at low flow rates. READ MORE

  5. 18. Allergenic Oxidation Products from Fragrance Terpenes. Chemical Analysis and Determination of Sensitizing Potency

    Author : Johanna Rudbäck; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Autoxidation; Contact allergy; Essential oils; Fragrances; Hydroperoxides; Ionization techniques; Mass spectrometry; Prehapten; Sensitization; Skin; Structure-activity relationships; Terpenes;

    Abstract : The ubiquitous presence of fragrance compounds in consumer products has resulted in a high frequency of contact allergy to fragrances in the population. For prevention purposes and according to EU regulations, cosmetics must be labeled when containing the most prominent fragrance allergens in concentrations exceeding 0. READ MORE

  6. 19. The Bronchoalveolar Lavage Proteome- Phenotypic associations to smoking and divergence towards development of COPD

    Author : Amelie Plymoth; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; mass spectrometry; proteomics; 2-D gel; COPD; bronchoalveolar lavage;

    Abstract : Proteomic analysis of bronchoalveolar lavage (BAL) fluid from smokers at risk of developing chronic obstructive pulmonary disease (COPD) and never smokers is described. COPD is currently the world's fourth leading cause of death and its prevalence is increasing. READ MORE

  7. 20. Analytical approaches to the study of mucin glycosylation

    Author : Kristina A Thomsson; Göteborgs universitet; []
    Keywords : mucins; O-linked glycosylation; mass spectrometry; cystic fibrosis; salivary mucins; sulfated oligosaccharides.;

    Abstract : Mucins constitute the major protein component of the mucus layer, which covers the epithelial surfaces of the respiratory, the gastrointestinal and the genitourinary tracts. Mucins carry O-linked oligosaccharides which contribute to the molecule by 50-80 weight percent, and these can be highly diverse, with 50-150 different oligosaccharides found on a purified mucin population. READ MORE