Search for dissertations about: "liver diabetes"

Showing result 1 - 5 of 186 swedish dissertations containing the words liver diabetes.

  2. 1. On leukocyte recruitment in endotoxemic liver injury

    Author : Daniel Klintman; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatology; Kirurgi; orthopaedics; Surgery; Sepsis; Liver; Inflammation; Adhesion; Endotoxemia; traumatologi;

    Abstract : Leukocyte recruitment is a key feature of liver injury associated with endotoxemia and systemic inflammation. The aim of this thesis was to define the adhesive mechanisms underlying leukocyte endothelial cell interactions, and the therapeutic potential of interference with specific adhesion molecules in endotoxemic liver damage. READ MORE

  4. 2. Effects of GH and liver-derived IGF-I on growth and metabolism

    Author : Klara Sjögren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GH; IGF-I; Insulin; GHRH; Somatostatin; GHS; Body growth; Body composition; Liver; Bone mineral content; Bone mineral density.;

    Abstract : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. READ MORE

  5. 3. Effects of a Paleolithic diet and exercise on liver fat, muscle fat and insulin sensitivity

    Author : Julia Otten; Tommy Olsson; Bo Angelin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; liver fat; Paleolithic diet; exercise training; insulin sensitivity; overweight; intramyocellular lipid content;

    Abstract : Finding ways to reduce risk for obesity-related disorders, including type 2 diabetes and cardiovascular disease, is important. Such approaches can include lifestyle interventions by diet and exercise. Our ancestors in the Paleolithic Era ate a diet based on vegetables, fruit, berries, lean meat, fish, seafood, nuts and eggs. READ MORE

  6. 4. Genetic variants for liver fat accumulation and circulating triglyceride levels

    Author : Ivana Stojkovic; Diabetes - kardiovaskulär sjukdom; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NAFLD; genetic variations; triglycerides; ALAT; dietary intake; type 2 diabetes; cardiovascular disease;

    Abstract : Non-alcoholic fatty liver disease (NAFLD), obesity and type 2 diabetes(T2D) are strongly associated and today their prevalence reaches epidemic proportions. NAFLD has a multi-factorial aetiology, both genetic and environmental factors are equally important. READ MORE

  7. 5. Integrating multi-omics for type 2 diabetes : Data science and big data towards personalized medicine

    Author : Klev Diamanti; Jan Komorowski; Claes Wadelius; Manfred Grabherr; Peter Spégel; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; multi-omics; genomics; metabolomics; data science; machine learning; personalized medicine; Bioinformatics; Bioinformatik;

    Abstract : Type 2 diabetes (T2D) is a complex metabolic disease characterized by multi-tissue insulin resistance and failure of the pancreatic β-cells to secrete sufficient amounts of insulin. Cells recruit transcription factors (TF) to specific genomic loci to regulate gene expression that consequently affects the protein and metabolite abundancies. READ MORE