Search for dissertations about: "liver size"

Showing result 1 - 5 of 84 swedish dissertations containing the words liver size.

  2. 1. Colorectal Cancer Liver Metastases : Effects of Chemotherapy on Liver Parenchyma and Resections

    Author : Jozef Urdzik; Agneta Norén; Per Hellman; James O Garden; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Current multimodal treatment of colorectal cancer liver metastasis often combines liver resections with preoperative chemotherapy with a 5-year survival of 40-50%. Preoperative chemotherapy includes conversion of initially non-resectable situation and control of micrometastatic disease. READ MORE

  4. 2. Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

    Author : Magnus Ölander; Per Artursson; Pär Matsson; Edward L. LeCluyse; Volker Lauschke; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; drug disposition; ADMET; drug transport; drug metabolism; hepatotoxicity; small intestine; liver; caco-2; human hepatocytes; cryopreservation; apoptosis; liver zonation; non-parenchymal cells; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : To reach the bloodstream, an orally administered drug must be absorbed through the small intestine and avoid extensive clearance in the liver. Estimating these parameters in vitro is therefore important in drug discovery and development. READ MORE

  5. 3. Interstitial Laser Thermotherapy of Liver Tumours. Methodology and Application

    Author : Páll Helgi Möller; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Resection; Liver; Neoplasm; Blood flow; Monitoring; Feedback control; Light penetration; Bare fibre; Sapphire probe; Nd:YAG laser; Interstitial thermotherapy; Hyperthermia; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : Interstitial laser thermotherapy (ILT) is a method well suited for selective local destruction of malignant tumours. In the present work, a laser thermotherapy system based on feedback temperature control of energy delivery (through computerised feedback system) was developed. READ MORE

  6. 4. Liver metastases from colorectal cancer

    Author : Jennie Engstrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Introduction: Colorectal cancer (CRC) is the third most common cancer worldwide. At diagnosis of CRC 20-25% of patients have metastatic disease. The liver is the most common metastatic site and liver metastases are detected in 25-30% of all patients. READ MORE

  7. 5. Coagulation in liver failure : the role of thromboelastometry and fibrinogen

    Author : Gabriel Dumitrescu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Liver failure is undeniably accompanied by distortions of the coagulation system. The modern theory of coagulation in patients with compensated liver disease (acute or chronic) states that the coagulation system is in a rebalanced state, also displaying prothrombotic tendencies particularly towards the end stages. READ MORE