Search for dissertations about: "liver stiffness"

Showing result 1 - 5 of 8 swedish dissertations containing the words liver stiffness.

2. 1. Ultrasound based shear wave elastography of the liver : a non-invasive method for evaluation of liver disease

   Author : Marie Byenfeldt; Anders Elvin; Per Fransson; Odd Helge Gilja; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthropometric measurement; diagnostic imaging; elasticity imaging technique; blood supply; BMI; body position; fatty liver; liver disease; hepatic steatosis; liver fibrosis; liver stiffness; obesity; postural change; pressure; probe; sex characteristic; shear wave elastography; skin-to-liver capsule distance; transducer and ultrasonography; Radiography; radiografi;

   Abstract : Background: Detecting liver disease at an early stage is important, given that early intervention decreases the risk of developing cirrhosis and subsequently hepatocellular cancer (HCC). The non-invasive ultrasound-based shear wave elastography (SWE) has been used clinically for a decade to assess liver stiffness. READ MORE

4. 2. Resection of colorectal liver metastases - Impact of preoperative chemotherapy

   Author : Sam Eriksson; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal liver metastases; Preoperative chemotherapy; Liver resection; Hepatic microcirculation; Sarcopenia;

   Abstract : Background Colorectal cancer is a leading cause of cancer related death worldwide. 20-30 % of patients will develop colorectal liver metastases (CRLMs). Surgical resection is the mainstay of treatment for CRLMs, and is often combined with perioperative chemotherapy, which can prolong progression-free survival after resection. READ MORE

5. 3. From fatty liver to end-stage liver disease through type 2 diabetes

   Author : Karl Björkström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The past decades have seen a marked increase in the incidence of type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). Epidemiological studies have clearly demonstrated that there is an association between type 2 diabetes and NAFLD. READ MORE

6. 4. Impact of Host Genetic Variants on Natural History and Treatment of Hepatitis C Virus Infection

   Author : Karolina Rembeck; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis C; prognostic factors;

   Abstract : Chronic hepatitis C Virus (HCV) infection causes liver disease and may progress to severe fibrosis, cirrhosis, and hepatocellular carcinoma. This thesis aimed to evaluate the impact of host genetics, i.e. READ MORE

7. 5. Translational Tumor Drug Delivery : Doxorubicin formulation performance, intracellular uptake and molecular diffusion

   Author : Oliver Degerstedt; Hans Lennernäs; Erik Sjögren; Per Hansson; Jessica Rosenholm; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; doxorubicin; drug diffusion; cellular uptake; drug delivery; PBPK modelling; hepatocellular carcinoma; emulsion; IC50; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Globally, hepatocellular carcinoma (HCC) is the most common form of liver cancer and a leading cause of cancer death. One important risk factor is liver cirrhosis and the disease progression is characterized by deposition of extracellular matrix proteins that form a fibrous network, which increases liver stiffness and may limit the effectiveness of different treatment strategies. READ MORE