Search for dissertations about: "lns"

Showing result 1 - 5 of 14 swedish dissertations containing the word lns.

  1. 1. Biomarker mRNAs for staging and prognosis of colorectal cancer

    University dissertation from Umeå : Umeå university

    Author : Lina Ohlsson; Marie-Louise Hammarström; John Shively; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; immunologi; Immunology;

    Abstract : Mesenteric lymph node (ln) metastasis is the single most important prognostic characteristic in colorectal cancer (CRC). The ln status is used for staging and is a decisive selection criterion for postoperative adjuvant therapy. However, it is difficult to accurately determine ln status by routine histopathology (H&E). READ MORE

  2. 2. Immune mechanisms that determine the quality of antibody responses to vaccines

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Author : Gustaf Lindgren; Karolinska Institutet.; Karolinska Institutet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Effective vaccines for many dangerous infectious diseases are still lacking. An improved understanding of the mechanisms that determine the quality of vaccine responses is essential to guide future attempts to design effective vaccines. READ MORE

  3. 3. Effects of intestinal worms on skin immunity and control of co-infection

    University dissertation from Stockholm : Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biology

    Author : Cajsa Classon; Karolinska Institutet.; Karolinska Institutet.; [2020]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Intestinal helminth infections remain a major health concern in developing areas of the world. Consequences of infection range from gastrointestinal discomfort to systemic manifestations. It has been suggested that individuals infected with intestinal helminths are more susceptible to other infections and mount weaker immunity to vaccination. READ MORE

  4. 4. Innate immune responses in vivo after antigen administration : implications for vaccine development

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Huddinge

    Author : Frank Liang; Karolinska Institutet.; Karolinska Institutet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Inducing high magnitude of antibodies with epitope breadth over prolonged periods of time is likely a prerequisite to prevent several of the world’s most serious infectious diseases such as HIV-1, malaria and tuberculosis for which there are no vaccines yet. A much better understanding of the innate immune mechanisms that are critical for inducing strong responses to vaccination is therefore essential. READ MORE

  5. 5. Expression, recognition and usage of laminin-8 (a4b1g1, Lm-411) by monocytes and neutrophils

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Zenebech Wondimu; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Basement membrane; laminins; myeloid cells; extravasation; migration.;

    Abstract : Laminins (LNs) are a family of large alphabetagamma heterotrimeric glycoproteins found in all basement membranes (BMs). They are expressed in a tissue- and developmental stagespecific manner and implicated in vital cellular functions, including cell adhesion, migration and signaling. READ MORE