Search for dissertations about: "long non-coding RNAs"
Showing result 11 - 15 of 35 swedish dissertations containing the words long non-coding RNAs.
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11. Deciphering the complexity of psoriasis : non-coding RNAs and cellular interactions
Abstract : Psoriasis is a prevalent immune-mediated skin disorder marked by chronically relapsing inflammation and epidermal hyperproliferation. As researchers delve deeper into the molecular intricacies of psoriasis, emerging evidence hints at the roles of non-coding RNAs (ncRNAs). READ MORE
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12. Ancient roles of non-coding RNAs in eukaryotic evolution : contributions from social amoebae and other protists
Abstract : RNAs not coding for proteins, non-coding RNAs (ncRNAs) have many important roles in all kingdoms of life. Especially in eukaryotes, the regulatory functions of ncRNAs have been suggested as a major force in the evolution of complex traits. READ MORE
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13. Non-coding RNA-based therapeutics and biomarkers for treatment and detection of vascular disease
Abstract : Cardiovascular disease (CVD), with atherosclerosis as its main underlying pathology, is the most prominent cause of death worldwide. Progression and rupture of atherosclerotic plaques lead to potential adverse pathological events such as myocardial infarction and stroke. READ MORE
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14. Genetic and Genomic Analysis of DNA Sequence Variation
Abstract : The studies in this thesis describe the application of genotyping and allele specific expression analysis to genetic studies. The role of the gene NPC1 in Triglyceride metabolism was explored in mouse models and in humans on the population level in study I. READ MORE
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15. miRNA and Asymmetric siRNA : Small RNAs with Large Effects on Bone Metabolism
Abstract : RNA interference (RNAi) is a post-transcriptional gene silencing process elicited by double-stranded RNA, such as micro-RNA (miRNA) and small interfering RNA (siRNA). They are 18-25 nucleotide long, small non-coding RNAs acting as critical regulators in eukaryotic genome expression. READ MORE