Search for dissertations about: "long non-coding RNAs"

Showing result 6 - 10 of 35 swedish dissertations containing the words long non-coding RNAs.

  2. 6. Functional analysis of long non-coding RNAs in cancer

    Author : Linda Vidarsdottir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : For years the functional role of noncoding RNAs was greatly underestimated. Whole genome RNA sequencing projects that unraveled pervasive transcription emitting from large parts of the human genome changed those perspectives and prompted scientists to further look into the involvement of noncoding RNAs (ncRNAs) in development and disease. READ MORE

  4. 7. Long non-coding RNAs in the epigenetic regulation of oligodendrocyte differentiation

    Author : Samudyata Samudyata; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Long non-coding RNAs (lncRNAs) constitute a heterogeneous class of RNAs with limited coding potential, united by an arbitrarily placed cut off of >200 ntd. The past decade has seen the emergence of lncRNAs as versatile regulators of gene expression, amidst skepticism regarding the biological usefulness of pervasive genomic transcription and its non-coding RNA products prevalent in most eukaryotes. READ MORE

  5. 8. Long non-coding RNAs and cellular interactions : investigating underlying mechanisms of oncogenesis

    Author : Jason T Serviss; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer is a leading cause of death worldwide with one in 8 men and one in 11 women dying from the disease (World Health Organization, 2018). Despite vast improvements in cancer diagnosis and therapy, the global cancer burden continues to rise in unison with population growth and longevity. READ MORE

  6. 9. The role of non-coding single-stranded oligonucleotides on Respiratory syncytial virus infection

    Author : Sandra Axberg Pålsson; Anna-Lena Spetz; Annika Karlsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Respiratory syncytial virus RSV ; single-stranded oligonucleotide ssON ; small non-coding RNA sncRNA ; nucleolin; virus infection; antiviral; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Respiratory syncytial virus (RSV) is an enveloped RNA virus of the Pneumoviridae family. RSV is reported to infect host cells by receptor-mediated endocytosis, also called clathrin-dependent endocytosis. Many reports indicate that the virus utilizes the host receptor nucleolin for entry. READ MORE

  7. 10. Characterization of Epstein-Barr virus non-coding RNAs in infected cells

    Author : Guojiang Xie; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EBV; EBV-associated malignancies; viral gene expression pattern; RPMS1; EBERs; single-cell sequencing; ChIRP; immune evasion; protein synthesis;

    Abstract : Epstein-Barr virus (EBV) causes multiple types of lymphoid and epithelial malignancies. Unraveling the viral gene expression patterns in tumors and identifying interaction partners between EBV and host elements is crucial for understanding EBV tumorigenesis. READ MORE