Search for dissertations about: "loss differentiation"
Showing result 1 - 5 of 282 swedish dissertations containing the words loss differentiation.
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1. Derivation, propagation and differentiation of human stem and progenitor cells
Abstract : Neuronal loss is a common feature of many neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease and traumatic brain injury. Human embryonic stem cells (hESCs) and hESC-derived neural progenitors (NPs) may provide a number of new ways for studying and treating diseases and injuries in the brain. READ MORE
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2. Stem Cell Plasticity Controlling Neuronal Differentiation Prior to Cell Transplantation
Abstract : Parkinson's disease (PD) is the second most common neurodegenerative disease and affects 2% of the population over 65 years of age. The disease is characterized by the progressive loss of dopaminergic neurons. Over time, symptoms increase and, in particular, lead to a dramatic slowness of movements. READ MORE
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3. Proteolytic processing of the Alzheimer APP protein family during neuronal differentiation
Abstract : Increased amyloid-β (Aβ) load in the brain, neurite degeneration, neuronal loss, and decreased levels of several neurotrophins are among the characteristics of Alzheimer’s disease (AD). Generation of Aβ occurs when the amyloid precursor protein (APP) is proteolytically processed by β- and γ-secretases in the amyloidogenic pathway. READ MORE
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4. Functional analysis of Ipf1/Pdx1, MFng and Id during pancreatic growth and differentiation
Abstract : The pancreas is an endodermally derived organ consisting of three major cell lineages. The endocrine cells, organised into the Islets of Langerhans, regulate blood glucose homeostasis by producing and secreting hormones such as glucagon and insulin into the bloodstream. READ MORE
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5. NEURAL STEM/PROGENITOR CELLS IN THE POST-ISCHEMIC ENVIRONMENT: Proliferation, Differentiation and Neuroprotection
Abstract : Stroke is one of the leading causes of chronic disability and death in the Western world. Today, no treatment can repair the cellular loss associated with an ischemic lesion. READ MORE