Search for dissertations about: "low molecular weight"

Showing result 1 - 5 of 325 swedish dissertations containing the words low molecular weight.

  1. 1. Protein Interaction Studies with Low Molecular Weight Ligands : Applications for Drug Discovery, Basic Research and Diagnostic Tool Design

    Author : Tony Christopeit; U.Helena Danielson; Danièle Altschuh; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : In this thesis, the interactions between different proteins and small ligands were characterized by surface plasmon resonance spectroscopy (SPR) and fluorescence resonance energy transfer (FRET) based assays.   For the C-reactive protein (CRP), a new type of artificial binder was identified which allows designing diagnostic assays superior to commonly used standard assays. READ MORE

  2. 2. Ligand binding and enzyme catalysis studied by molecular dynamics simulations

    Author : Tomas Hansson; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; molecular dynamics simulation; free energy; linear response; drug design; empirical valence bond; HIV protease; protein tyrosine phosphatase; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Molecular dynamics simulations and free energy calculations can be applied to biomolecular systems to predict ligand binding affinities. Combined with hybrid quantum-classical potential energy surfaces, such computations can also be used to probe enzymatic catalysis mechanisms. READ MORE

  3. 3. Synthesis of low molecular weight carbohydrates

    Author : Ingemar Kvarnström; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Kolhydrater;

    Abstract : .... READ MORE

  4. 4. Towards bacterial valorization of low molecular weight lignin

    Author : Krithika Ravi; Institutionen för kemiteknik; []
    Keywords : Pseudomonas putida; Microbacterium sp.; Guaiacol; Syringate; Kraft lignin; Bioconversion; Biorefineries;

    Abstract : Lignin is one of the major constituents in lignocellulosic biomass and is the mostabundant source of renewable aromatics on terrestrial ecosystems. The workcarried out in this thesis concerns bacterial conversion of low molecular weightlignin. READ MORE

  5. 5. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota

    Author : Lovisa Heyman; Molekylär nutrition; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; obesity; type 2 diabetes; berries; low-grade inflammation; gut microbiota; hepatic steatosis; gene expression; DNA methylation; lingonberry; blackcurrant; bilberry; açai;

    Abstract : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. READ MORE