Search for dissertations about: "low-density lipoprotein receptor"

Showing result 1 - 5 of 55 swedish dissertations containing the words low-density lipoprotein receptor.

2. 1. Effects of growth hormone on cardiovascular risk factors and atherosclerosis

   Author : Maria Leonsson Zachrisson; Göteborgs universitet; []
   Keywords : growth hormone; pituitary deficiency; dietary fat; cholesterol; low density; lipoprotein; intima-media thickness; IL-6; CRP; TNF-á;

   Abstract : Hypopituitary patients with growth hormone (GH) deficiency (GHD) have increasedmorbidity and mortality from cardiovascular disease (CVD). GH treatment has both beneficialand potentially negative cardiovascular effects. READ MORE

4. 2. Mechanisms for and consequences of cellular lipid accumulation - Role of the Very Low Density Lipoprotein (VLDL) receptor

   Author : Jeanna Perman; Göteborgs universitet; []
   Keywords : very low density lipoprotein receptor; lipid accumulation;

   Abstract : Lipid accumulation in non adipose tissue is associated with various cases of tissue dysfunction and tissue failure. Reduced availability of oxygen is known to cause intracellular lipid accumulation in cardiomyocytes as well as in hearts. READ MORE

5. 3. CXCL16 and CD137 in atherosclerosis

   Author : Dick Wågsäter; Allan Sirsjö; Ewa Ehrenborg; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; atherosclerosis; chemokine; cytokine; endothelial cells; inflammation; low-density lipoprotein; macrophages; scavenger receptor; smooth muscle cells; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

   Abstract : Atherosclerosis is a progressive inflammatory disease that is characterized by the accumulation of lipids, infiltrated cells and fibrous elements in large arteries. This thesis focuses on the molecular mechanisms behind foam cell formation and inflammation, two central processes in the development of atherosclerosis. READ MORE

6. 4. Studies on scavenger receptor class B type I and genes implicated in foam cell formation

   Author : Per-Arne Svensson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; scavenger receptor class B type I; high-density lipoprotein; oxidized low-density lipoprotein; macrophages; expression profiling;

   Abstract : The risk of atherosclerosis correlates with plasma levels of low-density lipoprotein (LDL) cholesterol and is inversely correlated to plasma levels of high-density lipoprotein (HDL) cholesterol. Accumulation of oxidized LDL (oxLDL) by arterial macrophages is a key event in the development of atherosclerosis. READ MORE

7. 5. Platelet-activating factor and lysophospatidylcholine in oxidized low density lipoprotein-mediated immune activation

   Author : Yihui Huang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : atherosclerosis; oxidized LDL; platelet-activating factor PAF ; Iysophosphatidylcholine LPC ; anti-MHC class II antibodies; antibody; T cells; cytokine; IFN-[gamma]; IL-6; IL-4; TNF-[alpha]; a PAF specific receptor antagonist-WEB2170;

   Abstract : Inflammation is a risk factor for development of cardiovascular disease, as in addition to known risk factors such as hypertension, hyperlipidemia, smoking and diabetes. Patients with inflammatory diseases including SLE have an enhanced risk of cardiovascular disease. READ MORE