Search for dissertations about: "low-dose CT"

Showing result 1 - 5 of 25 swedish dissertations containing the words low-dose CT.

2. 1. Biomarkers of ionising radiation relevant to carcinogenesis : Dose, dose rate and LET dependency of the responses

   Author : Milagrosa López Riego; Andrzej Wojcik; Lovisa Lundholm; Alexandros G. Georgakilas; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ionising radiation; low dose; low dose rate; linear energy transfer LET ; mixed beams; dose and dose rate effectiveness factor DDREF ; cancer; DNA damage response; biomarkers; molekylär biovetenskap; Molecular Bioscience;

   Abstract : A better understanding of the relationship between ionising radiation (IR) dose, dose rate and radiation quality, and the risk of stochastic effects would improve risk extrapolation from atomic bomb survivors’ data. Owing to insufficient statistical power of epidemiological studies to detect excess incidence of cancer following low doses of IR delivered at low dose rates (LDLDR), as typically encountered in most common human exposure scenarios, radiobiological experiments are fundamental to describe the biological effectiveness of LDLDR and to define the underlying molecular mechanisms. READ MORE

4. 2. Adolescent Idiopathic Scoliosis. The Role of Low Dose Computed Tomography

   Author : Kasim Abul-Kasim; Malmö Diagnostisk radiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; low-dose spine CT; effective dose; screw misplacement; adolescent idiopathic scoliosis; outcome.; titanium screws; image quality; neurovascular complication; phantom;

   Abstract : Continuous implementation of new operative methods for correction and stabilization of spinal deformities in young patients with AIS demands a detailed morphological analysis of the vertebral column. CT spine according to protocols available in daily clinical practice means high radiation dose to these young individuals. READ MORE

5. 3. CT Urography : Efforts to Reduce the Radiation Dose

   Author : Pär Dahlman; Anders Magnusson; Anders Sundin; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract malignancy; renal cell carcinoma; urography; x-ray computed tomography; radiation dosage; dose escalation; hematuria diagnosis; Diagnostic radiology; Diagnostisk radiologi; Radiologi; Radiology;

   Abstract : Computed tomography urography (CTU) is today the imaging method used to investigate patients with suspected urinary tract malignancy, replacing the old imaging method intravenous pyelography (IVP) about a decade ago. The downside of this shift was that the effective radiation dose to the examined patient was eight times higher for CTU compared to IVP. READ MORE

6. 4. Neonatal Exposure to Low-Dose Ionizing Radiation in Mice : Developmental Neurotoxic Effects of Single and Fractionated Doses and Interaction with Nicotine

   Author : Sonja Buratovic; Per Eriksson; Jack Valentin; Uppsala universitet; []
   Keywords : ;

   Abstract : This thesis aims to investigate the developmental neurotoxic effects of low-dose exposure to ionizing radiation, alone or together with nicotine, during a defined critical period of neonatal brain development in mice. Investigation of neurotoxic effects following fractionated or acute low-dose radiation, resembling the clinical situation during repeated CT scans or radiation delivered to non-target tissue during radiotherapy, and possible interaction effects with other agents, is of great importance for risk and safety evaluation. READ MORE

7. 5. Low-Dose Ionizing Radiation Induces Neurotoxicity in the Neonate : Acute or fractionated doses and interaction with xenobiotics in mice

   Author : Sonja Buratovic; Per Eriksson; Henrik Viberg; Bo Stenerlöw; Anders Fredriksson; Jean-René Jourdain; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ionizing radiation; Neonatal; Neurotoxicity; Behaviour; Nicotine; Ketamine; Mouse; Cognition; Acute irradiation; Fractionated irradiation;

   Abstract : This thesis examines the developmental neurotoxic effects of exposure to low-dose ionizing radiation (IR), alone or together with xenobiotics, during a critical period of neonatal brain development in mice.During mammalian brain development there is a period called the brain growth spurt (BGS), which involves extensive growth and maturation of the brain. READ MORE