Search for dissertations about: "low-molecular weight heparin"

Showing result 1 - 5 of 29 swedish dissertations containing the words low-molecular weight heparin.

  2. 1. Clinical aspects on treatment of deep venous thrombosis with a low molecular weight heparin

    Author : Margareta Holmström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Dalteparin is a low molecular weight heparin (LMWH) with a mean mw of 4-6000 D. Compared to unfractionated heparin (UFH), a higher bioavailability, a longer half-life and a more predictable dose-response is achieved after subcutaneous injections. READ MORE

  4. 2. Lipoprotein lipase in hemodialysis patients and healthy controls : effects of heparin

    Author : Birgit Näsström; Per-Ola Attman; Umeå universitet; []
    Keywords : dalteparin; dialysis; lipoprotein metabolism; LMWH; LPL; triglycerides; UFH; uremia; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

    Abstract : Mortality from cardiovascular disease in patients on chronic hemodialysis (HD) is 10 to 20 times greater than in the general population. One major risk factor is renal dyslipidemia, characterised by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. READ MORE

  5. 3. Endothelial and cardiac effects of 5-fluorouracil. An experimental and clinical study

    Author : Sara Kinhult; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; endothelin; onkologi; Cytologi; cancer; von Willebrand factor; thrombomodulin; lipoperoxidation; probucol; low-molecular weight heparin; scanning electron microscopy; 5-fluorouracil; endothelium;

    Abstract : The cytostatic drug 5-fluorouracil (5-FU) has been shown to affect both morphology and function of vascular endothelium. These effects could be part of the pathophysiology for 5-FU induced cardiotoxicity. The present thesis explores the mechanisms of this endothelial toxicity. READ MORE

  6. 4. Multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease

    Author : Tomas Jernberg; Uppsala universitet; []
    Keywords : Medical sciences; ST-monitoring; electrocardiography; vectorcardiography; myocardial infarction; unstable angina; prognosis; low-molecular-weight heparin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : This study evaluated the use of multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease (UCAD).At continuous 12-lead ECG (c12ECG), the definition of an ischemic episode as a transient ST-deviation ¡Ý0 for at least 1 minute resulted in a good observer agreement (kappa=0. READ MORE

  7. 5. Oral anticoagulation and stroke risk

    Author : Vilhelm Sjögren; Anders Själander; Per Wester; Peter J Svensson; Mia von Euler; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; warfarin; atrial fibrillation; dabigatran; rivaroxaban; apixaban; low-molecular-weight heparin; bridging;

    Abstract : Background: The risk of ischaemic stroke in patients with atrial fibrillation (AF) and mechanical heart valve (MHV) prostheses can be reduced by oral anticoagulation (OAC), which increases the risk of serious bleeding. The aims of this thesis were [1] to find out how effective and safe warfarin is where treatment quality is high, i.e. READ MORE