Search for dissertations about: "lumefantrine"

Showing result 1 - 5 of 17 swedish dissertations containing the word lumefantrine.

  1. 1. Development and Validation of Bioanalytical Methods Application to Melatonin and Selected Anti-Infective Drugs

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Susanne Römsing; Uppsala universitet.; Högskolan Dalarna.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Analytical Chemistry; Analytisk kemi; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography;

    Abstract : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. READ MORE

  2. 2. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Daniel Blessborn; Uppsala universitet.; Högskolan Dalarna.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Malaria; Chloroquine; Quinine; Sulfadoxine; Pyrimethamine; Mefloquine; Lumefantrine; Amodiaquine; Pyronaridine; Proguanil; Atovaquone; Sampling paper; Dried blood spots; Capillary blood; Antimalarial drugs; Solid-phase extraction; Liquid chromatography.;

    Abstract : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. READ MORE

  3. 3. The molecular basis of Plasmodium falciparum resistance to the antimalarial lumefantrine

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Christin Sisowath; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Malaria control is compromised by the development and spread of Plasmodium falciparum resistance to antimalarial drugs, which has caused an increase in malaria related morbidity and mortality. Artemisinin based combination therapy (ACT) has been implemented in almost all malaria endemic areas in an attempt to suppress drug resistance. READ MORE

  4. 4. The role of molecular markers in emerging artemether-lumefantrine resistant Plasmodium falciparum

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Author : Maja Malmberg; Karolinska Institutet.; Karolinska Institutet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Malaria is a devastating disease which kills ~1 million people yearly. The vast majority of lives lost due to malaria are children and pregnant women in sub-Saharan Africa. Although malaria is a treatable disease it continues to be one of the major causes of death, especially in poor settings. READ MORE

  5. 5. Effect of local food on lumefantrine bioavailability and population pharmacokinetics in Ugandan children with malaria

    University dissertation from Stockholm : Karolinska Institutet, Dept of Laboratory Medicine

    Author : Norah Mwebaza; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background. Artemether-lumefantrine (AL) is widely adopted as first-line treatment for uncomplicated malaria. Lumefantrine (LUM), the long acting partner drug is critical for cure by eliminating malaria parasites left after artemether exposure. READ MORE