Search for dissertations about: "lumican"

Showing result 1 - 5 of 7 swedish dissertations containing the word lumican.

2. 1. The role of leucine-rich repeat glycoproteins/proteoglycans in the assembly of collagen matrices

   Author : Liz Svensson; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; decorin; Collagen; fibromodulin; extracellular matrix; lumican; collagen fibrillogenesis; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Biokemi; Metabolism;

   Abstract : The properties of different connective tissues depend on the synthesis and assembly of macromolecular structures composed of collagen and other extracellular matrix components. Mechanisms modulating these events play important roles in the formation of a functional tissue. READ MORE

4. 2. Studies on the extracellular matrix of the dysfunctional pelvic floor

   Author : Marie Westergren Söderberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Pelvic floor; pelvic organ prolapse; stress urinary incontinence; extracellular matrix; collagen; SLRPs; decorin; lumican; fibromodulin; elastin associated proteins; fibrillin-1; fibulin-5; sex steroid hormone receptors; ER; PR; AR;

   Abstract : Objective: Pelvic floor dysfunction cause impaired quality of life of many women and is one of the most common reasons for gynaecological surgery on benign indications. Little is known about the pelvic floor extracellular matrix as a pre-requisite for mechanical sustainability through vaginal delivery, age and hormonal changes. READ MORE

5. 3. Biomarkers and surgical predictors in temporomandibular joint disease

   Author : Mattias Ulmner; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Temporomandibular joint (TMJ) disc displacement (DD) is associated with pain and impaired function and has two main sub-diagnoses, DD with or without reduction (DDwR/DDwoR). DD synovial tissue has been sparsely investigated, and further characterisation is needed. READ MORE

6. 4. Functions of small leucine-rich repeat proteoglycans in connective tissues

   Author : Sebastian Kalamajski; Åke Oldbergs forskargrupp; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Biological properties of connective tissues rely heavily on collagen and its use in formation of extracellular networks (matrices) in which cells can live and move. To regulate the process of collagen matrix assembly, the cells secrete small leucine-rich repeat proteoglycans (SLRPs) that bind to collagen and influence its fibril formation. READ MORE

7. 5. Extracellular matrix in atherosclerotic plaques: its role in plaque stability

   Author : Christoffer Tengryd; Kardiovaskulär forskning - translationella studier; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix; Laminin; Collagen; Proteoglycans; Atherosclerosis; Carotid plaque; TGF-β;

   Abstract : Atherosclerosis is a systemic disease affecting the large arteries caused by the accumulation of lipids in the vessel wall. Cardiovascular disease due to atherosclerosis is today the most common cause of death globally through its end consequences: myocardial infarctions and stroke. READ MORE