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Found 5 swedish dissertations matching the above criteria.

  1. 1. Prevention of Postoperative Duodenal Ileus by COX-2 Inhibition Improves Duodenal Function in Anaesthetised Rats

    Author : John Sedin; Olof Nylander; Markus Sjöblom; Lars Fändriks; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; duodenum; motility; enteric nervous system; luminal alkalinisation; CFTR; VIP; luminal Cl-; fluid secretion; solute absorption; mucosal permeability; 51Cr-EDTA; luminal osmolality; luminal hypertonicity; glucose; mannitol; orange juice; parecoxib; hexamethonium; mecamylamine; Physiology; Fysiologi;

    Abstract : Abdominal surgery inhibits gastrointestinal motility, a phenomenon referred to as postoperative ileus. Since the postoperative ileus disturbs duodenal physiology it is important to minimize the side effects of this condition. READ MORE

  2. 2. Luminal Hypotonicity and Duodenal Functions : An Experimental Study in the Rat

    Author : Liselotte Pihl; Olof Nylander; Gunnar Flemström; Mats Jodal; Uppsala universitet; []
    Keywords : Physiology; luminal alkalinization; mucosal permeability; osmolality; cyclooxygenase-2; rat; duodenum; jejunum; motility; enteric nervous system; Fysiologi;

    Abstract : After drinking water, the fluid quickly leaves the stomach thereby creating a hypotonic luminal environment in the duodenum. This in turn constitutes a potential threat to the integrity of the duodenal epithelium. It therefore seems highly likely that luminal hypotonicity activates physiological mechanisms that aim to increase luminal osmolality. READ MORE

  3. 3. Membrane transport and the human small intestine : Relation to mucosal protection, intestinal anaphylaxis and nitric oxide

    Author : Tina W. Knutson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; albumin; bicarbonate secretion; carbonic anhydrase; dopamine; duodenum; histamine; humans; hyaluronan; intestinal anaphylaxis; intestinal obstruction; jejunum; lidocaine; LOC-I-GUT; nitecapone; nitric oxide; potential difference; prostaglandins; segmental intestinal perfusion; Kirurgi; Surgery; Kirurgi; anestesiologi; Anaesthesiology;

    Abstract : The tightly adherent monolayer of epithelial cells that line the luminal side of the intestine provides a dynamic and highly regulated barrier to the passive and active transport of ions, water and macromolecules. Cathecol-O-methyl transferase inhibition prevents tissue degradation of catecholaminesincluding dopamine and intracellular carbonic anhydrase activity is an important regulator of ion and water transport in the small intestine. READ MORE

  4. 4. Regulation of Duodenal Mucosal Barrier Function and Motility : The Impact of Melatonin

    Author : Anna Sommansson; Markus Sjöblom; Olof Nylander; Oliver Bachmann; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; bicarbonate secretion; duodenum; enteric nervous system; enterochromaffin cell; ethanol; hexamethonium; in vivo; mecamylamine; motility; mucosal permeability; parecoxib; rat; Physiology; Fysiologi;

    Abstract : The duodenal mucosa is regularly exposed to acid, digestive enzymes and ingested noxious agents. It is thus critical to maintain a protective barrier to prevent the development of mucosal injury and inflammation, which are often observed in situations when barrier function is impaired. READ MORE

  5. 5. Sleep and cardiovascular health in women : the Stockholm female coronary risk study

    Author : Constanze Leineweber; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cardiovascular disease; prognosis; sleep; women;

    Abstract : Background: Both sleep disturbances and snoring has been related to an increased mortality and CHD risk. However, despite the fact that women report sleep difficulties more often than men, most studies have been done in men. A large amount of the studies is of cross-sectional character and no conclusions about cause and effect can be drawn. READ MORE