Search for dissertations about: "lung differentiation thesis"

Showing result 1 - 5 of 70 swedish dissertations containing the words lung differentiation thesis.

  2. 1. Influence of hypoxia on differentiation and proliferation of non-malignant and tumor cells

    Author : Marica Vaapil; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hypoxia; breast cancer; EPOR; small cell lung carcinoma; differentiation; proliferation; metabolism;

    Abstract : Solid tumors are less oxygenated than their tissue of origin. Low intra-tumor oxygen levels are associated with worse outcome, increased metastatic potential and immature phenotype in breast cancer. We have reported that tumor hypoxia correlates to low differentiation status in breast cancer. READ MORE

  4. 2. Anaplastic lymphoma kinase activity, a therapeutic target, suppresses neuroblastoma cell differentiation

    Author : Joachim T. Siaw; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; ALK; 11q.; DLG2; SP1; differentiation; crizotinib; ceritinib; brigatinib;

    Abstract : Neuroblastoma (NB) is the most common extracranial pediatric solid malignancy caused by the failed differentiation of precursor cells of the developing sympathetic nervous system. NB accounts for about 15% of childhood cancer-related deaths. READ MORE

  5. 3. C/EBP transcription factors in lung cellular differentiation and development

    Author : Tove Berg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : C EBP transcription factors; lung; development; differentiation; glucocorticoid regulation;

    Abstract : During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute the adult lung. READ MORE

  6. 4. Nuclear medicine imaging of lung cancer and esophagus cancer

    Author : Gunnar Herlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Lung cancer;

    Abstract : Background: Somatostatin receptors (SSTRs) occur in cancer tissue, and 99mTc-depreotide is a labelled somatostatin receptor analogue, binding to SSTRs subtype 2, 3, and 5. Purpose: The general aim of the present thesis was to study somatostatin receptor scintigraphy (SSTRS) with 99mTc-depreotide in the diagnosis and characterization of cancers in the lung and oesophagus. READ MORE

  7. 5. Revisiting cell specification and differentiation in the Drosophila airways, an insect organ homologous to our lung and blood vessels

    Author : Ryo Matsuda; Christos Samakovlis; Payre Francois; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cell differentiation; airways; Drosophila; cell signaling; transcription factors; utvecklingsbiologi; Developmental Biology;

    Abstract : Oxygen is essential for life. Aquatic ancestral animal species are thought to have independently terrestrialized and invented distinct strategies for efficient oxygen supply. The respiratory system of vertebrates like us is composed of lungs connected to the vasculature while insects have a single system delivering air directly to internal tissues. READ MORE