Search for dissertations about: "lung metastasis"

Showing result 1 - 5 of 34 swedish dissertations containing the words lung metastasis.

  2. 1. LRIG1 in lung cancer : prognostic effects and mechanistic studies

    Author : Samuel Kvarnbrink; Mikael Johansson; Håkan Hedman; Odd Terje Brustugun; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; metastasis; prognosis; LRIG1; LRIG3; LMO7; LIMCH1; Oncology; onkologi;

    Abstract : Lung cancer is the leading cause of cancer-related death worldwide as well as in Sweden. Non-small cell lung cancer (NSCLC) is the predominant form, which is largely subdivided into adenocarcinomas and squamous cell carcinomas. READ MORE

  4. 2. Lung Metastases - Diagnostic, Prognostic and Molecular Aspects with Focus on Colorectal Cancer

    Author : Halla Vidarsdottir; Förbättrad diagnostik och prognostik vid lungcancer och metastaser till lunga; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; lung metastasis; tissue microarray; TTF-1; napsin A; cytokeratin; GATA3; CDX2; PAX8; CRC; pulmonary metastasectomy; RBM3; recurrence; survival; NGS; Trusight tumor 26; Trusight Oncology 500;

    Abstract : In Sweden 4200 patients are diagnosed with lung cancer and 6500 patients with colorectal cancer (CRC) annually. The lungs are a common site for metastases. Immunohistochemistry (IHC) is a helpful aid in diagnostics of a pulmonary tumour. READ MORE

  5. 3. Wnt-5a signaling in breast cancer metastasis

    Author : Annette Säfholm; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; patologisk anatomi; General pathology; cancer; onkologi; Cytologi; breast cancer; Wnt-5a; migration; pathological anatomy; metastasis; signal transduction; peptides; Cytology; cancerology; oncology;

    Abstract : Breast cancer is the most common form of malignancy affecting women in the Western world. Today, anticancer treatment can control primary breast tumors, but treatment and prevention of metastatic disease still represents a major challenge in the management of breast cancer patients. READ MORE

  6. 4. Heparan sulfate dependent cell signaling and associated pathophysiology : Implications in tumorigenesis and embryogenesis

    Author : Tahira Batool; Jin-Ping Li; Aristidis Moustakas; Liliana Schaefer; Ingvar Ferby; Michael Welsh; Anders Malmström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Glucuronyl-C5 epimerase; Heparan Sulfate; Heparin; Lung Cancer; Cancer cell Singling; TGF-Beta; BMP; VEGF; Notch Signaling; Tumor growth; Metastasis; embryonic development; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Heparan sulfate proteoglycans (HSPGs) consist of a protein core to which several linear, negatively charged heparan sulfate (HS) chains are covalently attached. HSPGs are expressed on the cell surface and in the extra-cellular matrix (ECM) where they have diverse biological functions, for example co-receptor functions. READ MORE

  7. 5. Breast Cancer Biomarkers with Clinical Relevance Identified by Massively-parallel DNA and RNA Sequencing

    Author : Malin Dahlgren; Translational Oncogenomics; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; DNA sequencing; RNA sequencing; Metastasis; Biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2; Breast cancer; DNA sequencing; RNA sequencing; metastasis; biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2;

    Abstract : Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties. READ MORE