Search for dissertations about: "lupus nephritis"

Showing result 1 - 5 of 22 swedish dissertations containing the words lupus nephritis.

  2. 1. Lupus Nephritis – Genetic Impact on Clinical Phenotypes, Disease Severity and Renal Outcome

    Author : Karin Bolin; Gunnel Nordmark; Lars Rönnblom; Inger Gjertsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic Lupus Erythematosus; Nephritis; Lupus Nephritis; Genetics; STAT4; BANK1; C1q Deficiency; Renal Insufficiency; End-Stage Renal Disease; Sex Differences; Medicinsk vetenskap; Medical Science;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease that can affect every organ system. Lupus nephritis (LN) is one of the more serious SLE manifestations. Whilst the genetic background of SLE has been thoroughly investigated, less is known about the background of LN. READ MORE

  4. 2. Studies on lupus nephritis

    Author : Agneta Zickert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease characterized by multiple organ involvement, production of autoantibodies to nuclear components and local formation or deposition of immune complexes in different organs. Lupus nephritis (LN) is a common and severe manifestation of SLE. READ MORE

  5. 3. Genetic studies on Systemic Lupus Erythematosus : A fine mapping and candidate gene approach

    Author : Veronica Magnusson; Jerry Lanchbury; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Systemic Lupus Erythematosus; complex disease; linkage analysis; candidate gene; association studies; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

    Abstract : Linkage in the 2q37 region was evaluated using microsatellite markers in multi-case families from Sweden, Iceland and Norway. Both the two-point and the multipoint linkage analysis show highly significant LOD scores (Z=4.51 and 6.03, respectively). READ MORE

  6. 4. SLE : pathogenetic mechanisms in nephritis and sulphasalazine-induced lupus reactions

    Author : Iva Gunnarsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : systemic lupus erythematosus; IgA nephropathy; rheumatoid arthritis; anti-C1q antibodies; nephritis; C1q; IL-10; drug-induced; sulphasalazine;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune disease with a multifactorial and largely unknown etiology, in which genetic and environmental factors are known to influence disease susceptibility and expression. Nephritis is a common and severe disease manifestation in which immune complexes and complement deposits in the renal tissue are invariably seen. READ MORE

  7. 5. B cell depleting therapy in systemic lupus erythematosus

    Author : Thórunn Jónsdóttir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Systemic Lupus Erythematosus; Lupus nephritis; B cells; rituximab;

    Abstract : Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease characterized by multiple organ involvement, production of a wide range of autoantibodies and local formation or tissue deposition of immune complexes in the affected organs. Lupus nephritis (LN) is a common and serious organ involvement in patients with SLE. READ MORE