Search for dissertations about: "luzindole"

Found 4 swedish dissertations containing the word luzindole.

  2. 1. Effects of Orexins, Guanylins and Feeding on Duodenal Bicarbonate Secretion and Enterocyte Intracellular Signaling

    Author : Magnus Wilhelm Bengtsson; Gunnar Flemström; Olof Nylander; Karl E. O. Åkerman; Per M. Hellström; Uppsala universitet; []
    Keywords : Physiology; alkaline secretion; carbohydrates; central nervous system; cholinergic stimulation; duodenum; enteric nervous system; enterochromaffin cell; fasting; feeding; glucose; guanylyl cyclase C; humans; hypocretin; intra-arterial; in situ; intracerebroventricular; luminal acid; luzindole; orexin-B; SB-334867; Fysiologi;

    Abstract : The duodenal epithelium secretes bicarbonate ions and this is regarded as the primary defence mechanism against the acid discharged from the stomach. For an efficient protection, the duodenum must also function as a sensory organ identifying luminal factors. READ MORE

  4. 2. The Duodenal Mucosal Bicarbonate Secretion : Role of Melatonin in Neurohumoral Control and Cellular Signaling

    Author : Markus Sjöblom; Gunnar Flemström; Olof Nylander; Karl EO Åkerman; Per M. Hellström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; alkaline secretion; central nervous system; duodenal enterocyte; duodenal ulcer; duodenum; enterochromaffin cell; human; intraarterial; intracellular calcium; intracerebroventricular; melatonin; rat; vagal nerve; Fysiologi; Physiology; Fysiologi;

    Abstract : The duodenal lumen is exposed to aggressive factors with a high potential to cause damage to the mucosa. Bicarbonate secretion by the duodenal mucosa is accepted as the primary important defense mechanism against the hydrochloric acid intermittently expelled from the stomach. READ MORE

  5. 3. Regulation of Duodenal Mucosal Barrier Function and Motility : The Impact of Melatonin

    Author : Anna Sommansson; Markus Sjöblom; Olof Nylander; Oliver Bachmann; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; bicarbonate secretion; duodenum; enteric nervous system; enterochromaffin cell; ethanol; hexamethonium; in vivo; mecamylamine; motility; mucosal permeability; parecoxib; rat; Physiology; Fysiologi;

    Abstract : The duodenal mucosa is regularly exposed to acid, digestive enzymes and ingested noxious agents. It is thus critical to maintain a protective barrier to prevent the development of mucosal injury and inflammation, which are often observed in situations when barrier function is impaired. READ MORE

  6. 4. Experimental Disruption of Intestinal Mucosal Homeostasis : Exploring the Protective Potential of Melatonin and Misoprostol

    Author : Karsten Peters; Markus Sjöblom; Hans Lennernäs; David Dahlgren; Åsa Keita; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intestinal barrier dysfunction; intestinal permeability; chemotherapy-induced mucositis; doxorubicin; 5-fluorouracil; apoptosis; proliferation; melatonin; misoprostol; Medicinsk vetenskap; Medical Science;

    Abstract : The intestinal mucosa serves as a protective layer that separates the intestinal contents from the underlying tissues. It restricts harmful substances, pathogens, and undigested particles from entering the bloodstream. READ MORE