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Showing result 11 - 15 of 255 swedish dissertations matching the above criteria.

  2. 11. Prognostic and predictive factors in colorectal cancer

    Author : Kristoffer Derwinger; Göteborgs universitet; []
    Keywords : colorectal cancer; prognosis; lymph nodes; lymph node ratio; MTHFR; cyclin E; TNM; staging; metastasis;

    Abstract : Aim: The aim of the thesis was to study prognostic and predictive factors in patients treated for colorectal cancer (CRC). Method: In paper I, a retrospective comparison was made between the patients treated in 1999 (n=180) with those treated in 2004 (n=175). READ MORE

  4. 12. Sentinel Node Biopsy in Breast Cancer : Clinical and Immunological Aspects

    Author : Jana de Boniface; Leif Bergkvist; Annika Håkansson; Omgo Nieweg; Uppsala universitet; []
    Keywords : Surgery; breast cancer; tumour immunology; sentinel node biopsy; CD3-zeta; CD28; Kirurgi;

    Abstract : The most important prognostic factor in breast cancer is the axillary lymph node status. The sentinel node biopsy (SNB) is reported to stage the axilla with an accuracy > 95 % in early breast cancer. Tumour-related perturbation of T-cell function has been observed in patients with malignancies, including breast cancer. READ MORE

  5. 13. Modern Staging in Primary Breast Cancer-aspects of micrometastatic disease in bone marrow and molecular profiles in lymph node metastases

    Author : Anna-Karin Falck; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; biomarker expression; lymph node metastases; relapse; molecular subtype classification; disseminated tumour cells; bone marrow; prognosis; mode of detection;

    Abstract : Breast cancer is a heterogeneous disease with variations in the biological profile and subsequent clinical prognosis. Molecular mechanisms for tumour progression are currently being explored in scientific settings, suggesting parallel evolution of tumour cells at primary and metastatic locations. READ MORE

  6. 14. Extratumoral effects of highly aggressive prostate cancer

    Author : Kerstin Strömvall; Anders Bergh; Sofia Halin Bergström; Göran Landberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; tumor instructed normal tissue; TINT; non-malignant prostate tissue; lymph nodes; lymph node metastasis; pre-metastatic niche; tumor microenvironment; tumor macroenvironment; tumor immunoediting; Dunning rat model of prostate cancer;

    Abstract : Prostate cancer (PC) is the most common cancer in Sweden. Most patients have slow growing tumors that will not cause them any harm within their lifetime, but some have aggressive tumors and will die from their disease. READ MORE

  7. 15. Retroperitoneal lymph node dissection for non-seminomatous germ cell tumour

    Author : Axel Gerdtsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: The Swedish and Norwegian Testicular Cancer Group (SWENOTECA) is a multidisciplinary collaboration with an aim to improve the testicular cancer care for patients in Sweden and Norway by publishing guidelines, include patients in the SWENOTECA register and promote research. In 2007, SWENOTECA initiated RETROP, a multicenter study on nonseminomatous germ cell tumour (NSGCT) patients that are operated with post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND). READ MORE