Search for dissertations about: "lymphocyte homing"

Showing result 1 - 5 of 14 swedish dissertations containing the words lymphocyte homing.

  2. 1. EFFECTOR T CELL HOMING TO THE SMALL INTESTINAL MUCOSA

    Author : Hanna Stenstad; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; Immunology; serology; homing; intestine; GALT; chemokine receptor; lymphocyte; serologi;

    Abstract : The intestinal mucosa, including the intestinal epithelium and underlying lamina propria (LP), contains a large number of effector/memory T cells that are thought to play a central role in the generation and maintenance of mucosal immune responses and in maintaining mucosal integrity. The work in this thesis investigates the mechanisms regulating effector T cell recruitment to the small intestinal mucosa focusing on the role of chemokine receptors in this process. READ MORE

  4. 2. Chemokines and Integrins in Lymphocyte Development and Localization

    Author : Jan Marsal; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; transplantation; serology; Immunology; homing; development; IEL; lymphocytes; chemokines; integrins;

    Abstract : The small intestine contains a large number of T lymphocytes within the single-layered epithelium that separates the gut lumen from the lamina propria. These intraepithelial T lymphocytes have potent cytolytic and immunoregulatory capacities, thought to be important for fighting infections, neoplastic growth, and sustaining epithelial integrity. READ MORE

  5. 3. T lymphocyte recruitment in Helicobacter pylori-associated diseases

    Author : Karin Enarsson; Göteborgs universitet; []
    Keywords : Helicobacter pylori; homing; T lymphocytes; gastric adenocarcinoma; regulatory T cells;

    Abstract : Helicobacter pylori (Hp) infection is associated with pronounced infiltration of granulocytes and lymphocytes into the gastric mucosa, resulting in active chronic gastritis that may develop into duodenal ulcer disease or gastric adenocarcinoma (GC). Infiltrating T cells play a major role in the pathology of these diseases, but the signals involved in recruitment of T cells from blood to H. READ MORE

  6. 4. Trafficking of Human Dendritic Cells and B cells in Helicobacter pylori-induced Gastritis

    Author : Malin Hansson; Göteborgs universitet; []
    Keywords : Helicobacter pylori; migration; homing; dendritic cells; B cells; gastric mucosa;

    Abstract : Infection with the bacterium Helicobacter pylori is widespread throughout the world, and is associated with development of gastric and duodenal ulcer disease as well as gastric adenocarcinoma and mucosa associated lymphoid tissue lymphoma. The infection generally leads to a large infiltration of immune cells, among them dendrite cells (DC) and IgA-secreting cells. READ MORE

  7. 5. Chemokine Receptor CCR9: Studies on the Generation and Localization of Gut Tropic Lymphocytes

    Author : Marcus Svensson Frej; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine; transplantation; serologi; CCR9; CCL25; chemokines; lymphocyte homing; Immunology; serology; Immunologi;

    Abstract : Lymphocytes are important mediators of adaptive immune responses. Naive T lymphocytes circulate in the blood and lymph between different secondary lymphoid organs in search for their specific antigen. READ MORE