Search for dissertations about: "lymphocyte subpopulations"

Showing result 1 - 5 of 18 swedish dissertations containing the words lymphocyte subpopulations.

2. 1. Human T-lymphocyte activation : interactions between lymphocytes and mitogenic or non-mitogenic lectins

   Author : Marie-Louise Dillner-Centerlind; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The aim of this investigation was to gain further insights in the mechanisms of T-lymphocyte activation by lectins. Interactions between the lectins and purified lymphocytes from human peripheral blood, were studied in the following respects: in vitro culture requirements for lectin induced DNA-synthesis, intercellular regulations of the mitogen response and binding of lectins to lymphocyte surface components. READ MORE

4. 2. Factors regulating lymphocyte development and peripheral activation

   Author : Anna Makowska; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; NKT cells; TFG beta; Treg; Immunologi; serologi;

   Abstract : Peripheral tolerance is regulated by different types of regulatory T cells, including CD1-restricted T cells and CD4+CD25+ regulatory T (Treg) cells. This thesis has focused on the interactions between T cells and antigen presenting cells (APCs) and the immunregulatory function of TGF-b as two important factors regulating differentiation and activation of T cells in the periphery. READ MORE

5. 3. The dimensions of human and murine CD8 T lymphocyte diversity

   Author : Anthonie Johan Zwijnenburg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The adaptive immune system generates and maintains a pool of CD8+ T cells with an almost limitless specificity with the purpose of maintaining homeostasis. Upon antigen encounter, CD8+ T cells undergo functional diversification and give rise to daughter cells. READ MORE

6. 4. Chronic hepatitis B : immunological, virological and clinical aspects in the natural course and during the combined prednisolone and interferon-alpha-2b therapy

   Author : Guo-Zhong Fei; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HBV; IgM and IgG anti-preS2; IgM anti-HBc; CD4 CD8 ratio; lymphocyte subpopulations; HBV DNA; ALT; chronic hepatitis; prednisolone; interferon-alpha;

   Abstract : The aims of this study were to characterize the IgM and IgG antibody responses to well-defined B-cell epitopes within the preS2 region of the HBV envelope proteins in sera from Chinese and Caucasian patients with chronic HBV infection in relation to viral load and liver disease activity. In addition, the effects of the combined prednisolone and interferon- alpha-2b therapy on these parameters, as well as on the peripheral lymphocyte subsets, were studied in Chinese patients with chronic hepatitis B. READ MORE

7. 5. Experimental studies of human fetal liver cells : in regard to in utero hematopoietic stem cell transplantation

   Author : Bim Lindton; Karolinska Institutet; Karolinska Institutet; []
   Keywords : In utero transplantation; fetal liver cells; mixed lymphocyte culture; CD3; CD56; HLA class II; parvovirus B 19 capsids; corticosteroids; cytotoxic drugs; colony formation.;

   Abstract : Successful in utero hematopoietic stem cell transplantation represents a potential step forward in the management of patients with severe inherited hematological, metabolic and immunological disorders. Animal data from a number of species have demonstrated evidence of engraftment, but to date the only effective in utero transplantations (IUTx) in humans have been performed in fetuses with severe immunodeficiencies, suggesting that the fetal immune system play a vital role in the success or failure of in utero transplantation. READ MORE