Search for dissertations about: "lymphocyte subsets"

Showing result 6 - 10 of 62 swedish dissertations containing the words lymphocyte subsets.

2. 6. Human cytotoxic lymphocyte differentiation in health and disease

   Author : Heinrich Schlums; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cytotoxic lymphocytes, comprising natural killer (NK) cells and CD8+ cytotoxic T cells, eradicate infected or malignant cells by release of lytic granules and alarm the immune system through production of pro-inflammatory cytokines and chemokines. NK cells and CD8+ T cells belong to different arms of the immune system, employing complementary strategies for target cell recognition. READ MORE

4. 7. Involvement of T lymphocyte subsets in the rejection of murine tumors by syngeneic or autologous hosts

   Author : Tao Wen; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The aim of this thesis is to study the requirement of CD4+ and CD8+ T Iymphocyte subset, CD28 costimulatory molecule and p56kk for the rejection of syngeneic tumor grafts, and the autochthonous tumors induced by Moloney murine sarcoma virus. It also addresses the role of CD4+ and CD8+ T subsets with regard to the polyomavirus persistence and tumor development. READ MORE

5. 8. HIV-1 infection in Tanzania : HIV antibody testing strategies and lymphocyte subset determinations

   Author : Willy Shileanga Kikoka Urassa; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HIV; antibody detection; alternative confirmatory strategy; lymphocyte subsets; Tanzania; Africa.;

   Abstract : The objectives of the studies that are reported in this thesis were to evaluate HIV antibody testing strategies and prognostic markers and to study inummological deterioration of HIV-1 infected individuals. Alternative testing strategies for confirmation of HIV seropositivity were evaluated using combinations of screening assays. READ MORE

6. 9. Chemokine Receptor CCR9: Studies on the Generation and Localization of Gut Tropic Lymphocytes

   Author : Marcus Svensson Frej; Immunologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine; transplantation; serologi; CCR9; CCL25; chemokines; lymphocyte homing; Immunology; serology; Immunologi;

   Abstract : Lymphocytes are important mediators of adaptive immune responses. Naive T lymphocytes circulate in the blood and lymph between different secondary lymphoid organs in search for their specific antigen. READ MORE

7. 10. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy

   Author : Louise Magnusson; Per-Ola Carlsson; Rosaura Casas; Ola Winqvist; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Hashimoto´s thyroiditis; Graves´ disease; autoimmune Addison´s disease; antigen-presenting cells; B cells; non-classical monocytes; NK cells; memory CD8 T cells; CDCP1; SLAMF1; inflammation; lymphocyte activation; pregnancy; β-cell function; C-peptide; plasma proteome; prolactin; prokineticin-1; glucagon; oral glucose tolerance test; mass cytometry; proximity extension assay; Medicinsk vetenskap; Medical Science; Klinisk immunologi; Clinical Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Abstract : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. READ MORE