Search for dissertations about: "lymphoma"

Showing result 16 - 20 of 350 swedish dissertations containing the word lymphoma.

  2. 16. Analysis of Immunoglobulin Genes and Telomeres in B cell Lymphomas and Leukemias

    Author : Sarah Walsh; Richard Rosenquist; Christer Sundström; Anna Laurell; Andreas Rosenwald; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; B cell lymphoma leukemia; mantle cell lymphoma; hairy cell leukemia; lymphoplasmacytic lymphoma; immunoglobulin genes; antigen selection; telomeres; cellular origin; somatic hypermutation; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : B cell lymphomas and leukemias are heterogeneous tumors with different cellular origins. Analysis of immunoglobulin (Ig) genes enables insight into the B cell progenitor, as Ig somatic hypermutation correlates with antigen-related B cell transit through the germinal center (GC). READ MORE

  4. 17. Survival and treatment related toxicity in classical Hodgkin lymphoma

    Author : Ingemar Lagerlöf; Daniel Molin; Graham Collins; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hodgkin lymphoma; combined modality; late effects; treatment toxicity; radiotherapy; chemotherapy; long-term; follow-up; relative survival; years of life lost; excess mortality; excess morbidity; Oncology; Onkologi;

    Abstract : Treating early-stage classical Hodgkin lymphoma (cHL) by adding radiotherapy to chemotherapy gives better disease control compared to chemotherapy only. With a low median age at diagnosis, the risk from cHL needs to be weighed against the risk of treatment toxicity. READ MORE

  5. 18. Follicular and Diffuse Large B-Cell Lymphoma - Studies of Primary Treatment and Prognostic Factors

    Author : Elisabeth Szekely; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diffuse large B-cell lymphoma; ; follicular lymphoma; ; prognostic factors; ; etoposide; chemotherapy regimen; seasonal variation; gender; watch and wait; rituximab monotherapy;

    Abstract : .... READ MORE

  6. 19. Mantle cell lymphoma strategies in primary treatment

    Author : Alexandra Albertsson Lindblad; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mantle cell lymphoma; registry data; Clinical Trial; Phase I; Clinical Trial; Phase II; rituximab; bendamustine; lenalidomid; ibrutinib; ADCC; in vitro model; TP53 mutations; watchful waiting; mantle cell lymphoma; real-world data; lenalidomide; rituximab; bendamustin; ibrutinib; ADCC; TP53 mutation; CDKN2A; NGS; MIPI; Watchful waiting;

    Abstract : Mantle cell lymphoma (MCL) is associated with poor prognosis due to an aggressive clinical course. Being a rare disease, there are few randomized trials in MCL and there is no defined golden standard in primary treatment. READ MORE

  7. 20. Anaplastic Lymphoma Kinase mutations and downstream signalling

    Author : Christina Schönherr; Ruth H Palmer; Aristidis Moustakas; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Anaplastic Lymphoma Kinase; oncogene; RTK; neuroblastoma; crizotinib; NVP-TAE684; gain-of-function; MYCN; transcription factor; small GTPase; Rap1; C3G; PC12 cells; neurite outgrowth; molecular cell biology; molekylär cellbiologi;

    Abstract : The oncogene Anaplastic Lymphoma Kinase (ALK) is a Receptor Tyrosine Kinase (RTK) and was initially discovered as the fusion protein NPM (nucleophosmin)-ALK in a subset of Anaplastic Large Cell Lymphomas (ALCL). Since then more fusion proteins have been identified in a variety of cancers. READ MORE