Search for dissertations about: "lymphopoiesis"

Showing result 1 - 5 of 19 swedish dissertations containing the word lymphopoiesis.

  2. 1. Cytokine Regulation of Hematopoietic Stem Cells and Lymphopoiesis

    Author : Natalija Buza-Vidas; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; lineage commitment; cytokines; lymphopoiesis; extracellulära vätskor; transplantation; hematopoietic stem cells;

    Abstract : Large numbers of blood cells need to be continuously replaced in order to sustain the crucial functions of the immune system, oxygen transport and blood clotting. The large diversity of cell types required to maintain the integrity of the blood system are all produced from blood forming or hematopoietic stem cells (HSCs). READ MORE

  4. 2. Roles of hematopoietin and cytokine tyrosine kinase receptors in early lymphopoiesis

    Author : Christina Jensen; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL -7; FLT3 Ligand; cytokines; lymphopoiesis; hematopoiesis; TSLP; apoptosis;

    Abstract : Cytokines have been shown to have important roles in lymphopoiesis. However, many questions remain unresolved. Among other, while the action of interleukin (IL)-7 in alpha beta T cell development in mouse seems to be largely mediated through permissive survival signaling, the possible permissive role of IL-7 in early B cell development is disputed. READ MORE

  5. 3. Immunomodulation by estrogen and estren

    Author : Ulrika Islander; Göteborgs universitet; []
    Keywords : estrogen receptor knock-out mice; estrogen; estren; estrogen receptor; lymphopoiesis; T cells; B cells; immunoglobulin; inflammation;

    Abstract : Estrogen affects the development and regulation of the immune system. Treatment of gonadectomized mice with estrogen results in suppression of T and B lymphopoiesis, as well as decreased delayed type hypersensitivity reaction, granulocyte mediated inflammation and levels of IL-6 in serum. READ MORE

  6. 4. Switching ON Fetal B Lymphopoiesis

    Author : Trine Kristiansen; Avdelningen för molekylär hematologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B-1 B cells; Lin28; Fetal hematopoietic stem cells;

    Abstract : B-1a cells are innate-like lymphocytes that develop primarily during fetal and neonatal life, whereas adult bone marrow (BM) hematopoietic stem cells (HSCs) preferentially give rise to follicular B-2 cells. Functioning at the interface of the innate and adaptive immune systems, B-1a cells provide a non-redundant first line of defense prior to the temporally delayed establishment of a B-2 cell response. READ MORE

  7. 5. Lin28b regulation of early-life B lymphopoiesis. A model system to study how self-reactive B cells develop in early life

    Author : Hugo Åkerstrand; Avdelningen för molekylär hematologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lin28b; Developmental Immunology; B-1 B cells; Self-reactivity; B cell development; Early-life;

    Abstract : .... READ MORE