Search for dissertations about: "lymphopoiesis"
Showing result 6 - 10 of 19 swedish dissertations containing the word lymphopoiesis.
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6. Modulation of estrogen receptors alpha and beta. Effects on the immune system
Abstract : Estrogen affects the development and function of the immune system. Gonadectomized mice treated with estrogen display suppressed T and B lymphopoiesis and inhibited T cell and granulocyte dependent inflammation, while mature B cells are stimulated to produce more immunoglobulins. READ MORE
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7. On the origin of B cells. Elucidating the Role of Tyrosine Kinase Receptors in B Cell Development
Abstract : B cells are essential cells that are part of the adaptive immune system with the capacity to produce antibodies against exogenous antigens. These cells are produced through a process called hematopoiesis, tightly regulated by extrinsic and intrinsic factors. READ MORE
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8. The Road to Maturity - Lineage Commitment in early Hematopoiesis
Abstract : The road to maturity – how do hematopoietic stem cells (HSC) differentiate into mature blood cells? The pathways of lineage commitment during normal hematopoiesis are of great significance in order to understand the underlying events that lead to leukemia, and to the design of proper treatments for prevention and remission of the disease. The route of hematopoiesis can be thought of as a hierarchical tree, with the rare HSCs at the top, transitioning down along the pathways as different progenitors. READ MORE
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9. In vivo and in vitro evolution of molecular mechanisms - Importance in B cell development and phage display
Abstract : Bone marrow resident hematopoietic stem cells differentiate into all different types of lymphoid populations, there among mature naive B cells expressing IgM and IgD. During the maturation, the B cells are subjected to several steps of selection to ensure proper development of the antigen receptor. READ MORE
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10. Hematopoiesis: Functional Insights by Cell Fate Conversion
Abstract : Blood cell formation, or hematopoiesis, is maintained by rare hematopoietic stem cells (HSCs) residing in the bone marrow (BM). HSCs may self-renew (the process whereby HSCs replicate to produce new HSCs) to preserve their own numbers, as well as initiate a highly coordinated hierarchical differentiation process that results in the production of mature effector blood cells. READ MORE