Search for dissertations about: "lysosomal membrane destabilization"

Found 2 swedish dissertations containing the words lysosomal membrane destabilization.

  2. 1. Oxidized Lipids and Lysosomal Pathology in Atherogenesis

    Author : Wei Li; Wendy Jessup; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Macrophages take up large amount of exogenous materials such as oxidatively modified low-density lipoproteins (oxLDL) and lysosomotropic agents. OxLDL is taken up into macrophage lysosomes through receptor-mediated endocytosis, but poorly degraded, resulting in foam cell formation. READ MORE

  4. 2. Prevention of oxidant-induced cell death by intralysosomal iron binding

    Author : Lennart Persson; Rolf Hultcrantz; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The lung is particularly prone to oxidative stress by its exposure to ambient oxygen and inhaled environmental oxidants. Abnormal assimilation and accumulation of iron are found in many lung disorders, which in redox-active form will exacerbate oxidative tissue damage. READ MORE