Search for dissertations about: "möss"

Showing result 11 - 15 of 237 swedish dissertations containing the word möss.

  2. 11. Intracellular mechanisms in rd1 mouse retinal degeneration

    Author : Leif Johnson; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; Neuroprotection; Photoreceptor; Retinitis Pigmentosa; Oftalmologi;

    Abstract : Retinitis pigmentosa (RP) is an inherited disorder and the leading cause of visual impairment in the working age population. It is caused by a number of different genetic mutations, all of which cause the rod photoreceptors to degenerate. As the rods become few in numbers, the cones will also begin to die, resulting in total blindness. READ MORE

  4. 12. Energy metabolism as a target for new treatment strategies in Huntington’s disease

    Author : Marie Sjögren; Biomarkörer vid hjärnsjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington´s disease; Energy metabolic alteration; Weight loss; Skeletal muscle; Adipose tissue; R6 2; Ghrelin; Liraglutide;

    Abstract : Huntington´s disease (HD) is a fatal inherited neurodegenerative disorder caused by a CAG triplet repeat expansion in the huntingtin (HTT) gene and characterized by cognitive and motoric dysfunctions as well as psychiatric problems. Accumulating evidence, however, suggests altered energy metabolism and a hyper-catabolic state as key features of HD pathology. READ MORE

  5. 13. Adaptive immune responses in atherosclerosis - or how to prolong the use of your yellow socks

    Author : Daniel Kolbus; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cationized BSA; Atherosclerosis; alum; CD8 T cell; intima-media thickness;

    Abstract : Abstract Atherosclerosis is a multifactorial disease, but an unbalanced immune system plays a critical role in the disease development. A common theory states that a continuous stress to the vascular vessel wall initiates a repair process that however is insufficient to completely heal the tissue. READ MORE

  6. 14. Cartilage proteins and their arthritogenic properties in arthritis

    Author : Stefan Carlsén; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; Immunology; HLA-DR4; tolerance; COMP; CXI; CIX; arthritis; Cartilage; collagen;

    Abstract : In this thesis the role of cartilage proteins and their potential as antigen and availability to the immune system in arthritis were investigated. Six papers are included; where four present new animal models for Rheumatoid arthritis (RA), one shows how genetic disorders in cartilage may affect arthritis and the last how posttranslational modification of collagen type II (CII) affects tolerance. READ MORE

  7. 15. T cells, Cytokines, and Genetic Factors in Autoimmunity Studies of experimental models of arthritis and sialadenitis

    Author : Åsa Johansson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; Collagen-induced arthritis Sialadenitis Mice Knockout Linkage analysis T cells Cytokines; muscle system; Skeleton; reumatologi; muskelsystem; Skelett;

    Abstract : To understand the pathogenesis of autoimmune diseases we have to consider the problem from different angles. Animal models provide a tool to further understand these complex diseases, as the influence of genetic and environmental factors could be limited. READ MORE