Search for dissertations about: "mAChRs"

Showing result 1 - 5 of 9 swedish dissertations containing the word mAChRs.

  2. 1. Amino acid transport and receptor binding properties in neuropsychiatric disorders using the fibroblast cell model

    Author : Jessica Johansson; Nikolaos Venizelos; Lars Oreland; Örebro universitet; []
    Keywords : Fibroblasts; Bipolar disorder; ADHD; Tyrosine; Tryptophan; Alanine; Transport; mAChRs; Biomedicin; Biomedicine;

    Abstract : Altered transport of the catecholamines and serotonin precursor amino acids tyrosine and tryptophan, might be one explanation for the dysfunctional neurotransmission implicated in the pathophysiology of bipolar disorder and Attention Deficit/Hyperactivity Disorder (ADHD). In previous studies, an altered amino acid transport has been found in schizophrenia and autism, when using the fibroblast cell model. READ MORE

  4. 2. Effects of ethanol on muscarinic acetylcholine receptors in nerve cells

    Author : Murielle Hellsten Caron; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; nerve cell; SH-SY5Y; NOS; PKC; PLC; Ethanol; mAChR;

    Abstract : This thesis focused on the mechanisms involved in the effects of long-term ethanol treatment on mAChRs and their coupled-signal transduction pathway in human neuroblastoma SH-SY5Y cells. All 5 subtypes of mAChRs were expressed in these cells. READ MORE

  5. 3. Influence of neuromodulators and mechanical loading on pathological cell and tissue characteristics in tendinosis

    Author : Gloria Fong; Patrik Danielson; Alex Scott; Ludvig Backman; Paul Ackermann; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; substance P; acetylcholine; transforming growth factor; neuromodulators; mechanical loading; tendinosis; anatomi; Human Anatomy;

    Abstract : Background: Tendinosis is a painful chronic, degenerative condition characterized by objective changes in the tissue structure of a tendon. Hallmark features in tendinosis tendons include increased number of cells (hypercellularity), extracellular matrix (ECM) degradation and disorganized collagen. READ MORE

  6. 4. Neuropeptides and neurotransmitters in keratocytes : importance in corneal wound healing processes

    Author : Marta Sloniecka; Patrik Danielson; May Griffith; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; substance P; acetylcholine; migration; proliferation; apoptosis; corneal stroma;

    Abstract : Background: The cornea is the outermost transparent layer of the eye and it is responsible for the majorityof the eye’s total focusing power. Keratocytes are the resident cells of the corneal stroma and their function isto produce extracellular matrix components and to take part in corneal healing after injury, which may occurdue to trauma, infection or surgery. READ MORE

  7. 5. Cholinergic receptors in human prenetal brain : presence, distribution and influence of nicotine and ethanol

    Author : Lena Falk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Events early in life, including exposure to various compounds, may cause disturbances in brain development. Both maternal smoking and alcohol drinking during pregnancy can induce preand postnatal death, cognitive and neurobehavioral disturbances. READ MORE