Search for dissertations about: "mRNA capping"

Found 2 swedish dissertations containing the words mRNA capping.

  1. 1. Targeting Infectious Disease : Structural and functional studies of proteins from two RNA viruses and Mycobacterium tuberculosis

    Author : Anna M. Jansson; T. Alwyn Jones; Sherry L. Mowbray; E. Yvonne Jones; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; RNA virus; coronavirus; alphacoronavirus; nsp1; TGEV; flavivirus; Modoc virus; NS5; methyltransferase; mRNA capping; Mycobacterium tuberculosis; tuberculosis; 1-deoxy-D-xylulose 5-phosphate reductoisomerase; DXR; fosmidomycin analogues; MEP pathway; drug development; xray-crystallography; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biokemi; Biochemistry; Medicinal Chemistry; Läkemedelskemi;

    Abstract : The recent emergence of a number of new viral diseases as well as the re-emergence of tuberculosis (TB), indicate an urgent need for new drugs against viral and bacterial infections.Coronavirus nsp1 has been shown to induce suppression of host gene expression and interfere with host immune response. READ MORE

  2. 2. Selective ADAR editing and the coordination with splicing

    Author : Annika Källman; Marie Öhman; Mary O’Connell; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Maturation of precursor messenger RNAs (pre-mRNA) in eukaryotes includes processes like capping, 3’ end formation and splicing. Some premRNAs undergo an additional process called RNA editing where a single nucleotide is modified to generate a new nucleotide identity. READ MORE