Search for dissertations about: "mTOR"
Showing result 16 - 20 of 100 swedish dissertations containing the word mTOR.
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16. Insights into the role of spinal mTOR in the modulation of inflammation and nociception
Abstract : Pain, especially chronic pain, is a major clinical problem. Pain therapy has proven to be complicated and the results are often unsatisfactory. Despite many years of research, the number of available pain therapeutics remains relatively small. READ MORE
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17. Nutrient and energy sensing in skeletal muscle
Abstract : Nutrient overload and physical inactivity often leads to the development of obesity and type 2 diabetes. Acute over-nutrition can induce insulin resistance, while physical exercise enhances skeletal muscle insulin sensitivity. Like every living cell, skeletal muscle senses nutrient and energy signals and to adjust metabolic flux. READ MORE
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18. Human muscle response to sprint exercise and nutrient supply with focus on factors related to protein metabolism
Abstract : The overall aim of the present thesis was to study the muscular response to repeated bouts of 30-s sprint exercise. This type of exercise gives rise to a profound metabolic perturbation that might counteract an exercise-induced stimulation of muscle protein synthesis. READ MORE
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19. Transcriptional regulation of ribosome biogenesis in skeletal muscle growth
Abstract : Resistance exercise induces skeletal muscle hypertrophy via repeated exercise bouts. The increased muscle protein synthesis together with altered muscle protein degradation contribute to the adaptation of muscle mass. The number of ribosomes dictates the protein synthetic capacity of muscle. READ MORE
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20. The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human Placenta
Abstract : Abnormal fetal growth, which is associated with both perinatal morbidity as well as metabolic diseases in adulthood, is an important clinical problem affecting as many as 15% of all pregnancies. However, to this date, there is no specific treatment of this condition. READ MORE