Search for dissertations about: "malaria cytokines"

Showing result 1 - 5 of 11 swedish dissertations containing the words malaria cytokines.

  2. 1. Studies on malaria blood stage infection and host responses

    Author : Lili Xu; Klavs Berzins; Adrian Luty; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; cytokines; parasite ligands; merozoite released soluble proteins MRSPs ; molekylär biovetenskap; Molecular Biosciences;

    Abstract : The challenges in controlling malaria infectious disease are increasing due to drug resistance and incomplete immunity induced by malaria infection. Moreover there is no effective vaccine available against malaria blood stage infection. READ MORE

  4. 2. Malaria during pregnancy and childhood : A focus on soluble mediators and neutrophils

    Author : Stéphanie Boström; Marita Troye-Blomberg; Maria Yazdanbakhsh; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plasmodium falciparum; pregnancy; childhood; neutrophils; biomarkers; cytokines; chemokines; antibodies; Fulani; Dogon; immunologi; Immunology;

    Abstract : In areas where malaria is endemic, pregnant women and children bear the main burden of severe and life-threatening malarial disease. The aim of this work was to study the impact of Plasmodium falciparum infection on inflammatory responses in pregnant women and children residing in African countries. READ MORE

  5. 3. Dissecting the complexity of human susceptibility to Plasmodium falciparum malaria: genetic approaches

    Author : Valentina D Mangano; Marita Troye-Blomberg; Marta Alarcon; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; genetics; malaria; Immunology; Immunologi; immunologi; Immunology;

    Abstract : There are many aspects of the immunology of P. falciparum infection that are not understood. Genetic approaches are of great value for dissecting the complexity of immune responses to malaria in natura by providing new insights into molecular interactions between the parasite and the host. READ MORE

  6. 4. T cell and antibody responses in Plasmodium falciparum malaria and their relation to disease susceptibility

    Author : Salah Eldin Farouk; Marita Troye-Blomberg; Hannah Akuffo; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; P. falciparum; Malaria; Granulysin; Fulani; Schizont; Immunology; Immunologi;

    Abstract : Malaria antigen-induced polarization of T cells into effectors Th1 and/or Th2 cells and their subsequent release of cytokines is known to affect antibody production. This thesis includes studies on early innate responses to the parasite, with a focus on γδT cells, and acquired specific responses in African sympatric ethnic tribes. READ MORE

  7. 5. Host genetic factors and antibody responses with potential involvement in the susceptibility to malaria

    Author : Elisabeth Israelsson; Klavs Berzins; Jean Langhorne; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunology; Immunologi; immunologi; Immunology;

    Abstract : The relatively lower susceptibility to malaria seen in the Fulani ethnic group in Africa, as compared to other sympatric ethnic groups, has been related to genetic regulation of the immune responses. This thesis aimed to describe important pathways related to the regulation of antibodies in the immune responses during a malaria infection. READ MORE