Search for dissertations about: "male reproductive function"

Showing result 1 - 5 of 50 swedish dissertations containing the words male reproductive function.

  2. 1. The impact of genetic, environmental and life-style factors on male reproductive function

    Author : Jonas Richthoff; Malmö Reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; male reproductive function; testicular cancer; smoking; Medicin människa och djur ; Medicine human and vertebrates ; cryptorchidism; sperm concentration;

    Abstract : Recent studies have indicated a decline in sperm number in the western world during the past 50 years, sperm concentration changing from 113 to 66 millions per mL. Furthermore, significant geographical differences in male reproductive function have been observed. READ MORE

  4. 2. Reproductive function in male childhood cancer survivors

    Author : Patrik Romerius; Malmö Reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood Cancer SurvivorsFertilityHypogonadismSperm DNA IntegrityAzoospermiaEstrogen Receptor alpha polymorphism;

    Abstract : Childhood cancer (CC) survival rate has increased over the last couple of decades, today approaching 80%. Therefore more attention has been paid to late effects. One important issue for CC survivors (CCS) is impaired reproductive function. READ MORE

  5. 3. Genetic, environmental and life-style effects on androgen receptor function

    Author : Christel Björk; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproductive function; smoking; 4 .4-DDE; persistent organic pollutants; prostate cancer; Androgen receptor; prostate specific antigen; CAG polymorphism; TCDD; aryl hydrocarbon receptor; CB-153;

    Abstract : Androgens regulate male reproductive function and their effects are mediated through the androgen receptor (AR). The AR gene contains a polymorphic CAG repeat, encoding a stretch of glutamines, affecting the transcriptional activity of the AR. READ MORE

  6. 4. Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies

    Author : Yasir Ruhayel; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytoplasmic and nuclear; Receptors; Prostatic neoplasms; genetic; Polymorphism; male; Infertility; Hypogonadism; Genetic association studies; Case–control studies; Androgens;

    Abstract : Androgen action plays a pivotal role in male reproductive tract physiology and pathology. The androgen receptor (AR) gene harbors two codon repeat tracts: the CAG and GGN repeats, encoding corresponding amino acid sequences of variable length; the polyglutamine and polyglycine stretches, respectively. READ MORE

  7. 5. THE ANDROGEN RECEPTOR GGN POLYMORPHISM. Genetic and functional analyses

    Author : Kristina Lundin; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Functional domain; Genetic predisposition; Reproductive function; Sex hormone; Transactivation function; Repeat; Polymorphism; Androgen receptor; Transcription factor; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Male sex development and reproductive function is regulated by androgens acting via the androgen receptor (AR). The AR harbours two polymorphic repeats of CAG and GGN triplets, encoding glutamines and glycines, respectively. READ MORE